GWAS for male-pattern baldness identifies 71 susceptibility loci explaining 38% of the risk

Male pattern baldness (MBP) is a complex trait that has genetic associations. Here, Pirastu and colleagues perform a genome-wide association study to show 71 susceptibility loci associated with MBP — 30 of which are novel — and that these loci can explain 38% of heritability.

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Autores principales:	Nicola Pirastu, Peter K. Joshi, Paul S. de Vries, Marilyn C. Cornelis, Paul M. McKeigue, NaNa Keum, Nora Franceschini, Marco Colombo, Edward L. Giovannucci, Athina Spiliopoulou, Lude Franke, Kari E. North, Peter Kraft, Alanna C. Morrison, Tõnu Esko, James F. Wilson
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/398ebcbfa0db4012bd0477df4ca9c6df
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spelling	oai:doaj.org-article:398ebcbfa0db4012bd0477df4ca9c6df2021-12-02T17:06:18ZGWAS for male-pattern baldness identifies 71 susceptibility loci explaining 38% of the risk10.1038/s41467-017-01490-82041-1723https://doaj.org/article/398ebcbfa0db4012bd0477df4ca9c6df2017-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01490-8https://doaj.org/toc/2041-1723Male pattern baldness (MBP) is a complex trait that has genetic associations. Here, Pirastu and colleagues perform a genome-wide association study to show 71 susceptibility loci associated with MBP — 30 of which are novel — and that these loci can explain 38% of heritability.Nicola PirastuPeter K. JoshiPaul S. de VriesMarilyn C. CornelisPaul M. McKeigueNaNa KeumNora FranceschiniMarco ColomboEdward L. GiovannucciAthina SpiliopoulouLude FrankeKari E. NorthPeter KraftAlanna C. MorrisonTõnu EskoJames F. WilsonNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Nicola Pirastu Peter K. Joshi Paul S. de Vries Marilyn C. Cornelis Paul M. McKeigue NaNa Keum Nora Franceschini Marco Colombo Edward L. Giovannucci Athina Spiliopoulou Lude Franke Kari E. North Peter Kraft Alanna C. Morrison Tõnu Esko James F. Wilson GWAS for male-pattern baldness identifies 71 susceptibility loci explaining 38% of the risk
description	Male pattern baldness (MBP) is a complex trait that has genetic associations. Here, Pirastu and colleagues perform a genome-wide association study to show 71 susceptibility loci associated with MBP — 30 of which are novel — and that these loci can explain 38% of heritability.
format	article
author	Nicola Pirastu Peter K. Joshi Paul S. de Vries Marilyn C. Cornelis Paul M. McKeigue NaNa Keum Nora Franceschini Marco Colombo Edward L. Giovannucci Athina Spiliopoulou Lude Franke Kari E. North Peter Kraft Alanna C. Morrison Tõnu Esko James F. Wilson
author_facet	Nicola Pirastu Peter K. Joshi Paul S. de Vries Marilyn C. Cornelis Paul M. McKeigue NaNa Keum Nora Franceschini Marco Colombo Edward L. Giovannucci Athina Spiliopoulou Lude Franke Kari E. North Peter Kraft Alanna C. Morrison Tõnu Esko James F. Wilson
author_sort	Nicola Pirastu
title	GWAS for male-pattern baldness identifies 71 susceptibility loci explaining 38% of the risk
title_short	GWAS for male-pattern baldness identifies 71 susceptibility loci explaining 38% of the risk
title_full	GWAS for male-pattern baldness identifies 71 susceptibility loci explaining 38% of the risk
title_fullStr	GWAS for male-pattern baldness identifies 71 susceptibility loci explaining 38% of the risk
title_full_unstemmed	GWAS for male-pattern baldness identifies 71 susceptibility loci explaining 38% of the risk
title_sort	gwas for male-pattern baldness identifies 71 susceptibility loci explaining 38% of the risk
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/398ebcbfa0db4012bd0477df4ca9c6df
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GWAS for male-pattern baldness identifies 71 susceptibility loci explaining 38% of the risk

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