Attempted suicide in bipolar disorder: risk factors in a cohort of 6086 patients.

<h4>Objective</h4>Bipolar disorder is associated with high risk of self-harm and suicide. We wanted to investigate risk factors for attempted suicide in bipolar patients.<h4>Method</h4>This was a cohort study of 6086 bipolar patients (60% women) registered in the Swedish Nati...

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Autores principales:	Dag Tidemalm, Axel Haglund, Alina Karanti, Mikael Landén, Bo Runeson
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2014
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/39933eb127784c8dbba6dcc056737585
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spelling	oai:doaj.org-article:39933eb127784c8dbba6dcc0567375852021-11-18T08:24:47ZAttempted suicide in bipolar disorder: risk factors in a cohort of 6086 patients.1932-620310.1371/journal.pone.0094097https://doaj.org/article/39933eb127784c8dbba6dcc0567375852014-01-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24705630/pdf/?tool=EBIhttps://doaj.org/toc/1932-6203<h4>Objective</h4>Bipolar disorder is associated with high risk of self-harm and suicide. We wanted to investigate risk factors for attempted suicide in bipolar patients.<h4>Method</h4>This was a cohort study of 6086 bipolar patients (60% women) registered in the Swedish National Quality Register for Bipolar Disorder 2004-2011 and followed-up annually 2005-2012. Logistic regression was used to calculate adjusted odds ratios for fatal or non-fatal attempted suicide during follow-up.<h4>Results</h4>Recent affective episodes predicted attempted suicide during follow-up (men: odds ratio = 3.63, 95% CI = 1.76-7.51; women: odds ratio = 2.81, 95% CI = 1.78-4.44), as did previous suicide attempts (men: odds ratio = 3.93, 95% CI = 2.48-6.24; women: odds ratio = 4.24, 95% CI = 3.06-5.88) and recent psychiatric inpatient care (men: odds ratio = 3.57, 95% CI = 1.59-8,01; women: odds ratio = 2.68, 95% CI = 1.60-4.50). Further, those with many lifetime depressive episodes were more likely to attempt suicide. Comorbid substance use disorder was a predictor in men; many lifetime mixed episodes, early onset of mental disorder, personality disorder, and social problems related to the primary group were predictors in women.<h4>Conclusion</h4>The principal clinical implication of the present study is to pay attention to the risk of suicidal behaviour in bipolar patients with depressive features and more severe or unstable forms of the disorder.Dag TidemalmAxel HaglundAlina KarantiMikael LandénBo RunesonPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 9, Iss 4, p e94097 (2014)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Dag Tidemalm Axel Haglund Alina Karanti Mikael Landén Bo Runeson Attempted suicide in bipolar disorder: risk factors in a cohort of 6086 patients.
description	<h4>Objective</h4>Bipolar disorder is associated with high risk of self-harm and suicide. We wanted to investigate risk factors for attempted suicide in bipolar patients.<h4>Method</h4>This was a cohort study of 6086 bipolar patients (60% women) registered in the Swedish National Quality Register for Bipolar Disorder 2004-2011 and followed-up annually 2005-2012. Logistic regression was used to calculate adjusted odds ratios for fatal or non-fatal attempted suicide during follow-up.<h4>Results</h4>Recent affective episodes predicted attempted suicide during follow-up (men: odds ratio = 3.63, 95% CI = 1.76-7.51; women: odds ratio = 2.81, 95% CI = 1.78-4.44), as did previous suicide attempts (men: odds ratio = 3.93, 95% CI = 2.48-6.24; women: odds ratio = 4.24, 95% CI = 3.06-5.88) and recent psychiatric inpatient care (men: odds ratio = 3.57, 95% CI = 1.59-8,01; women: odds ratio = 2.68, 95% CI = 1.60-4.50). Further, those with many lifetime depressive episodes were more likely to attempt suicide. Comorbid substance use disorder was a predictor in men; many lifetime mixed episodes, early onset of mental disorder, personality disorder, and social problems related to the primary group were predictors in women.<h4>Conclusion</h4>The principal clinical implication of the present study is to pay attention to the risk of suicidal behaviour in bipolar patients with depressive features and more severe or unstable forms of the disorder.
format	article
author	Dag Tidemalm Axel Haglund Alina Karanti Mikael Landén Bo Runeson
author_facet	Dag Tidemalm Axel Haglund Alina Karanti Mikael Landén Bo Runeson
author_sort	Dag Tidemalm
title	Attempted suicide in bipolar disorder: risk factors in a cohort of 6086 patients.
title_short	Attempted suicide in bipolar disorder: risk factors in a cohort of 6086 patients.
title_full	Attempted suicide in bipolar disorder: risk factors in a cohort of 6086 patients.
title_fullStr	Attempted suicide in bipolar disorder: risk factors in a cohort of 6086 patients.
title_full_unstemmed	Attempted suicide in bipolar disorder: risk factors in a cohort of 6086 patients.
title_sort	attempted suicide in bipolar disorder: risk factors in a cohort of 6086 patients.
publisher	Public Library of Science (PLoS)
publishDate	2014
url	https://doaj.org/article/39933eb127784c8dbba6dcc056737585
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Attempted suicide in bipolar disorder: risk factors in a cohort of 6086 patients.

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