AMPA receptors commandeer an ancient cargo exporter for use as an auxiliary subunit for signaling.

AMPA receptors commandeer an ancient cargo exporter for use as an auxiliary subunit for signaling.

Fast excitatory neurotransmission in the mammalian central nervous system is mainly mediated by ionotropic glutamate receptors of the AMPA subtype (AMPARs). AMPARs are protein complexes of the pore-lining α-subunits GluA1-4 and auxiliary β-subunits modulating their trafficking and gating. By a prote...

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Autores principales: Nadine Harmel, Barbara Cokic, Gerd Zolles, Henrike Berkefeld, Veronika Mauric, Bernd Fakler, Valentin Stein, Nikolaj Klöcker
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
Materias:
Medicine
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Science
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Acceso en línea:https://doaj.org/article/3995b600a67b43d9a7d4337429c02548
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