Prevalence of Neuroendocrine Tumors in the Gastrointestinal and Hepatobiliary Systems

Background: Carcinoid tumors are the most common neuroendocrine tumors. In recent years, these tumors have had an increasein incidence, which is probably due to a higher number of them being incidentally found as a result of the rise of preventivemedicine.Objectives: This study aimed to analyze a se...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Modesto J Varas Lorenzo, Fernando Munoz Agel, Ramon Abad Belando, Elena Mengual
Formato:	article
Lenguaje:	EN
Publicado:	Shiraz University of Medical Sciences 2019
Materias:	carcinoid tumors neuroendocrine tumor carcinoid syndrome colon rectum gastrointestinal system hepatobiliary system Medicine R
Acceso en línea:	https://doaj.org/article/39974d7e6f224b6891ea7a5913d1959a
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:39974d7e6f224b6891ea7a5913d1959a
record_format	dspace
spelling	oai:doaj.org-article:39974d7e6f224b6891ea7a5913d1959a2021-11-14T08:42:16ZPrevalence of Neuroendocrine Tumors in the Gastrointestinal and Hepatobiliary Systems2783-243010.5812/acr.88004.https://doaj.org/article/39974d7e6f224b6891ea7a5913d1959a2019-06-01T00:00:00Zhttps://colorectalresearch.sums.ac.ir/article_46322_6c26971273bdc67c6b06fb98eb3522a2.pdfhttps://doaj.org/toc/2783-2430Background: Carcinoid tumors are the most common neuroendocrine tumors. In recent years, these tumors have had an increasein incidence, which is probably due to a higher number of them being incidentally found as a result of the rise of preventivemedicine.Objectives: This study aimed to analyze a series of digestive carcinoid tumors detected by conventional endoscopy and/or echoendoscopyto evaluate the prevalence of those located in the colon and rectum, and subsequently make a comparison with data availablein the literature.Methods: In this retrospective, multicenter study (two centers), the clinical records of 100 white patients with more than 100 digestivecarcinoid tumors (some multiple) diagnosed from 1994 to 2018 were reviewed.Results: The mean age of presentation was 52 years and 57% of the patients were men. The mean tumor size was 10 mm. The localizationof the tumors was: stomach 43% (n = 43); duodenum 5% (n = 5); intestine 8% (n = 8); appendix 14% (n = 14); colon 4% (n = 4);rectum 19% (n = 19); pancreas 3% (n = 3); liver 2% (n = 2); gallbladder 1% (n = 1); primary tumor of unknown origin 1% (n = 1). Mostmultifocal tumors were in the stomach (20%; n = 20), followed by the duodenum (1%; n = 1) and intestine (1%; n = 1). Metastases andcarcinoid syndrome were observed in 6% and 5% of the cases, respectively. General survival at the closure of the study was 80%.Conclusions: Age and sex were similar to those described in the literature, while the colon and rectum represented 23% of all carcinoidtumors. There was a predominance of gastroduodenal and rectal carcinoid tumors, probably because the series analyzedwas essentially endoscopic. In comparison with the literature, less cases of metastases or carcinoid syndrome were recorded andsurvival was greater, perhaps due to earlier diagnosis and treatment.Modesto J Varas LorenzoFernando Munoz AgelRamon Abad BelandoElena MengualShiraz University of Medical Sciencesarticlecarcinoid tumorsneuroendocrine tumorcarcinoid syndromecolonrectumgastrointestinal systemhepatobiliary systemMedicineRENIranian Journal of Colorectal Research, Vol 7, Iss 2, Pp 1-7 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	carcinoid tumors neuroendocrine tumor carcinoid syndrome colon rectum gastrointestinal system hepatobiliary system Medicine R
spellingShingle	carcinoid tumors neuroendocrine tumor carcinoid syndrome colon rectum gastrointestinal system hepatobiliary system Medicine R Modesto J Varas Lorenzo Fernando Munoz Agel Ramon Abad Belando Elena Mengual Prevalence of Neuroendocrine Tumors in the Gastrointestinal and Hepatobiliary Systems
description	Background: Carcinoid tumors are the most common neuroendocrine tumors. In recent years, these tumors have had an increasein incidence, which is probably due to a higher number of them being incidentally found as a result of the rise of preventivemedicine.Objectives: This study aimed to analyze a series of digestive carcinoid tumors detected by conventional endoscopy and/or echoendoscopyto evaluate the prevalence of those located in the colon and rectum, and subsequently make a comparison with data availablein the literature.Methods: In this retrospective, multicenter study (two centers), the clinical records of 100 white patients with more than 100 digestivecarcinoid tumors (some multiple) diagnosed from 1994 to 2018 were reviewed.Results: The mean age of presentation was 52 years and 57% of the patients were men. The mean tumor size was 10 mm. The localizationof the tumors was: stomach 43% (n = 43); duodenum 5% (n = 5); intestine 8% (n = 8); appendix 14% (n = 14); colon 4% (n = 4);rectum 19% (n = 19); pancreas 3% (n = 3); liver 2% (n = 2); gallbladder 1% (n = 1); primary tumor of unknown origin 1% (n = 1). Mostmultifocal tumors were in the stomach (20%; n = 20), followed by the duodenum (1%; n = 1) and intestine (1%; n = 1). Metastases andcarcinoid syndrome were observed in 6% and 5% of the cases, respectively. General survival at the closure of the study was 80%.Conclusions: Age and sex were similar to those described in the literature, while the colon and rectum represented 23% of all carcinoidtumors. There was a predominance of gastroduodenal and rectal carcinoid tumors, probably because the series analyzedwas essentially endoscopic. In comparison with the literature, less cases of metastases or carcinoid syndrome were recorded andsurvival was greater, perhaps due to earlier diagnosis and treatment.
format	article
author	Modesto J Varas Lorenzo Fernando Munoz Agel Ramon Abad Belando Elena Mengual
author_facet	Modesto J Varas Lorenzo Fernando Munoz Agel Ramon Abad Belando Elena Mengual
author_sort	Modesto J Varas Lorenzo
title	Prevalence of Neuroendocrine Tumors in the Gastrointestinal and Hepatobiliary Systems
title_short	Prevalence of Neuroendocrine Tumors in the Gastrointestinal and Hepatobiliary Systems
title_full	Prevalence of Neuroendocrine Tumors in the Gastrointestinal and Hepatobiliary Systems
title_fullStr	Prevalence of Neuroendocrine Tumors in the Gastrointestinal and Hepatobiliary Systems
title_full_unstemmed	Prevalence of Neuroendocrine Tumors in the Gastrointestinal and Hepatobiliary Systems
title_sort	prevalence of neuroendocrine tumors in the gastrointestinal and hepatobiliary systems
publisher	Shiraz University of Medical Sciences
publishDate	2019
url	https://doaj.org/article/39974d7e6f224b6891ea7a5913d1959a
work_keys_str_mv	AT modestojvaraslorenzo prevalenceofneuroendocrinetumorsinthegastrointestinalandhepatobiliarysystems AT fernandomunozagel prevalenceofneuroendocrinetumorsinthegastrointestinalandhepatobiliarysystems AT ramonabadbelando prevalenceofneuroendocrinetumorsinthegastrointestinalandhepatobiliarysystems AT elenamengual prevalenceofneuroendocrinetumorsinthegastrointestinalandhepatobiliarysystems
_version_	1718429770344038400

Prevalence of Neuroendocrine Tumors in the Gastrointestinal and Hepatobiliary Systems

Ejemplares similares