Dazl is a target RNA suppressed by mammalian NANOS2 in sexually differentiating male germ cells

The Nanos family protein, NANOS2, is required for sexual differentiation of male germ cells in mice, however, the molecular RNA targets are unknown. Here, Kato et al. identify Dazl, a germ cell-specific gene, as being a target of NANOS, with stabilized DazlmRNA causing abnormal resumption of the cel...

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Autores principales:	Yuzuru Kato, Takeo Katsuki, Hiroki Kokubo, Aki Masuda, Yumiko Saga
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/399a28da6cd743b79022f96d019a8960
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id	oai:doaj.org-article:399a28da6cd743b79022f96d019a8960
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spelling	oai:doaj.org-article:399a28da6cd743b79022f96d019a89602021-12-02T14:38:35ZDazl is a target RNA suppressed by mammalian NANOS2 in sexually differentiating male germ cells10.1038/ncomms112722041-1723https://doaj.org/article/399a28da6cd743b79022f96d019a89602016-04-01T00:00:00Zhttps://doi.org/10.1038/ncomms11272https://doaj.org/toc/2041-1723The Nanos family protein, NANOS2, is required for sexual differentiation of male germ cells in mice, however, the molecular RNA targets are unknown. Here, Kato et al. identify Dazl, a germ cell-specific gene, as being a target of NANOS, with stabilized DazlmRNA causing abnormal resumption of the cell cycle.Yuzuru KatoTakeo KatsukiHiroki KokuboAki MasudaYumiko SagaNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Yuzuru Kato Takeo Katsuki Hiroki Kokubo Aki Masuda Yumiko Saga Dazl is a target RNA suppressed by mammalian NANOS2 in sexually differentiating male germ cells
description	The Nanos family protein, NANOS2, is required for sexual differentiation of male germ cells in mice, however, the molecular RNA targets are unknown. Here, Kato et al. identify Dazl, a germ cell-specific gene, as being a target of NANOS, with stabilized DazlmRNA causing abnormal resumption of the cell cycle.
format	article
author	Yuzuru Kato Takeo Katsuki Hiroki Kokubo Aki Masuda Yumiko Saga
author_facet	Yuzuru Kato Takeo Katsuki Hiroki Kokubo Aki Masuda Yumiko Saga
author_sort	Yuzuru Kato
title	Dazl is a target RNA suppressed by mammalian NANOS2 in sexually differentiating male germ cells
title_short	Dazl is a target RNA suppressed by mammalian NANOS2 in sexually differentiating male germ cells
title_full	Dazl is a target RNA suppressed by mammalian NANOS2 in sexually differentiating male germ cells
title_fullStr	Dazl is a target RNA suppressed by mammalian NANOS2 in sexually differentiating male germ cells
title_full_unstemmed	Dazl is a target RNA suppressed by mammalian NANOS2 in sexually differentiating male germ cells
title_sort	dazl is a target rna suppressed by mammalian nanos2 in sexually differentiating male germ cells
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/399a28da6cd743b79022f96d019a8960
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Dazl is a target RNA suppressed by mammalian NANOS2 in sexually differentiating male germ cells

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