A general mechanism of ribosome dimerization revealed by single-particle cryo-electron microscopy

When bacteria enter the stationary growth phase, protein translation is suppressed via the dimerization of 70S ribosomes into inactive complexes. Here the authors provide a structural basis for how the dual domain hibernation promotion factor promotes ribosome dimerization and hibernation in bacteri...

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Bibliographic Details
Main Authors: Linda E. Franken, Gert T. Oostergetel, Tjaard Pijning, Pranav Puri, Valentina Arkhipova, Egbert J. Boekema, Bert Poolman, Albert Guskov
Format: article
Language:EN
Published: Nature Portfolio 2017
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Online Access:https://doaj.org/article/399c1c026c834306bf7b09a8915fb0a1
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