Chitosan as an Underrated Polymer in Modern Tissue Engineering

Chitosan is one of the most well-known and characterized materials applied in tissue engineering. Due to its unique chemical, biological and physical properties chitosan is frequently used as the main component in a variety of biomaterials such as membranes, scaffolds, drug carriers, hydrogels and,...

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Autores principales:	Marta Kołodziejska, Kamila Jankowska, Marta Klak, Michał Wszoła
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	chitosan biopolymer biomedicine bioprinting 3D bio-ink Chemistry QD1-999
Acceso en línea:	https://doaj.org/article/399ce25c3c9946088bfcea63d38dc1b8
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spelling	oai:doaj.org-article:399ce25c3c9946088bfcea63d38dc1b82021-11-25T18:31:45ZChitosan as an Underrated Polymer in Modern Tissue Engineering10.3390/nano111130192079-4991https://doaj.org/article/399ce25c3c9946088bfcea63d38dc1b82021-11-01T00:00:00Zhttps://www.mdpi.com/2079-4991/11/11/3019https://doaj.org/toc/2079-4991Chitosan is one of the most well-known and characterized materials applied in tissue engineering. Due to its unique chemical, biological and physical properties chitosan is frequently used as the main component in a variety of biomaterials such as membranes, scaffolds, drug carriers, hydrogels and, lastly, as a component of bio-ink dedicated to medical applications. Chitosan’s chemical structure and presence of active chemical groups allow for modification for tailoring material to meet specific requirements according to intended use such as adequate endurance, mechanical properties or biodegradability time. Chitosan can be blended with natural (gelatin, hyaluronic acid, collagen, silk, alginate, agarose, starch, cellulose, carbon nanotubes, natural rubber latex, κ-carrageenan) and synthetic (PVA, PEO, PVP, PNIPPAm PCL, PLA, PLLA, PAA) polymers as well as with other promising materials such as aloe vera, silica, MMt and many more. Chitosan has several derivates: carboxymethylated, acylated, quaternary ammonium, thiolated, and grafted chitosan. Its versatility and comprehensiveness are confirming by further chitosan utilization as a leading constituent of innovative bio-inks applied for tissue engineering. This review examines all the aspects described above, as well as is focusing on a novel application of chitosan and its modifications, including the 3D bioprinting technique which shows great potential among other techniques applied to biomaterials fabrication.Marta KołodziejskaKamila JankowskaMarta KlakMichał WszołaMDPI AGarticlechitosanbiopolymerbiomedicinebioprinting3Dbio-inkChemistryQD1-999ENNanomaterials, Vol 11, Iss 3019, p 3019 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	chitosan biopolymer biomedicine bioprinting 3D bio-ink Chemistry QD1-999
spellingShingle	chitosan biopolymer biomedicine bioprinting 3D bio-ink Chemistry QD1-999 Marta Kołodziejska Kamila Jankowska Marta Klak Michał Wszoła Chitosan as an Underrated Polymer in Modern Tissue Engineering
description	Chitosan is one of the most well-known and characterized materials applied in tissue engineering. Due to its unique chemical, biological and physical properties chitosan is frequently used as the main component in a variety of biomaterials such as membranes, scaffolds, drug carriers, hydrogels and, lastly, as a component of bio-ink dedicated to medical applications. Chitosan’s chemical structure and presence of active chemical groups allow for modification for tailoring material to meet specific requirements according to intended use such as adequate endurance, mechanical properties or biodegradability time. Chitosan can be blended with natural (gelatin, hyaluronic acid, collagen, silk, alginate, agarose, starch, cellulose, carbon nanotubes, natural rubber latex, κ-carrageenan) and synthetic (PVA, PEO, PVP, PNIPPAm PCL, PLA, PLLA, PAA) polymers as well as with other promising materials such as aloe vera, silica, MMt and many more. Chitosan has several derivates: carboxymethylated, acylated, quaternary ammonium, thiolated, and grafted chitosan. Its versatility and comprehensiveness are confirming by further chitosan utilization as a leading constituent of innovative bio-inks applied for tissue engineering. This review examines all the aspects described above, as well as is focusing on a novel application of chitosan and its modifications, including the 3D bioprinting technique which shows great potential among other techniques applied to biomaterials fabrication.
format	article
author	Marta Kołodziejska Kamila Jankowska Marta Klak Michał Wszoła
author_facet	Marta Kołodziejska Kamila Jankowska Marta Klak Michał Wszoła
author_sort	Marta Kołodziejska
title	Chitosan as an Underrated Polymer in Modern Tissue Engineering
title_short	Chitosan as an Underrated Polymer in Modern Tissue Engineering
title_full	Chitosan as an Underrated Polymer in Modern Tissue Engineering
title_fullStr	Chitosan as an Underrated Polymer in Modern Tissue Engineering
title_full_unstemmed	Chitosan as an Underrated Polymer in Modern Tissue Engineering
title_sort	chitosan as an underrated polymer in modern tissue engineering
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/399ce25c3c9946088bfcea63d38dc1b8
work_keys_str_mv	AT martakołodziejska chitosanasanunderratedpolymerinmoderntissueengineering AT kamilajankowska chitosanasanunderratedpolymerinmoderntissueengineering AT martaklak chitosanasanunderratedpolymerinmoderntissueengineering AT michałwszoła chitosanasanunderratedpolymerinmoderntissueengineering
_version_	1718411008456785920

Chitosan as an Underrated Polymer in Modern Tissue Engineering

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