Chromatin conformation regulates the coordination between DNA replication and transcription
The maintenance of chromatin integrity during replication is critical for cell viability. Here the authors study how dividing cells respond to alterations in chromatin structure and find that these elicit a range of responses in the dynamics of DNA replication and consequences on replicative stress.
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Nature Portfolio
2018
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oai:doaj.org-article:399d7ceb0c43497db1da7ece90fc06c82021-12-02T16:50:10ZChromatin conformation regulates the coordination between DNA replication and transcription10.1038/s41467-018-03539-82041-1723https://doaj.org/article/399d7ceb0c43497db1da7ece90fc06c82018-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-03539-8https://doaj.org/toc/2041-1723The maintenance of chromatin integrity during replication is critical for cell viability. Here the authors study how dividing cells respond to alterations in chromatin structure and find that these elicit a range of responses in the dynamics of DNA replication and consequences on replicative stress.Ricardo AlmeidaJosé Miguel Fernández-JustelCristina Santa-MaríaJean-Charles CadoretLaura Cano-ArocaRodrigo LombrañaGonzalo HerranzAlessandra AgrestiMaría GómezNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-14 (2018) |
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Science Q Ricardo Almeida José Miguel Fernández-Justel Cristina Santa-María Jean-Charles Cadoret Laura Cano-Aroca Rodrigo Lombraña Gonzalo Herranz Alessandra Agresti María Gómez Chromatin conformation regulates the coordination between DNA replication and transcription |
description |
The maintenance of chromatin integrity during replication is critical for cell viability. Here the authors study how dividing cells respond to alterations in chromatin structure and find that these elicit a range of responses in the dynamics of DNA replication and consequences on replicative stress. |
format |
article |
author |
Ricardo Almeida José Miguel Fernández-Justel Cristina Santa-María Jean-Charles Cadoret Laura Cano-Aroca Rodrigo Lombraña Gonzalo Herranz Alessandra Agresti María Gómez |
author_facet |
Ricardo Almeida José Miguel Fernández-Justel Cristina Santa-María Jean-Charles Cadoret Laura Cano-Aroca Rodrigo Lombraña Gonzalo Herranz Alessandra Agresti María Gómez |
author_sort |
Ricardo Almeida |
title |
Chromatin conformation regulates the coordination between DNA replication and transcription |
title_short |
Chromatin conformation regulates the coordination between DNA replication and transcription |
title_full |
Chromatin conformation regulates the coordination between DNA replication and transcription |
title_fullStr |
Chromatin conformation regulates the coordination between DNA replication and transcription |
title_full_unstemmed |
Chromatin conformation regulates the coordination between DNA replication and transcription |
title_sort |
chromatin conformation regulates the coordination between dna replication and transcription |
publisher |
Nature Portfolio |
publishDate |
2018 |
url |
https://doaj.org/article/399d7ceb0c43497db1da7ece90fc06c8 |
work_keys_str_mv |
AT ricardoalmeida chromatinconformationregulatesthecoordinationbetweendnareplicationandtranscription AT josemiguelfernandezjustel chromatinconformationregulatesthecoordinationbetweendnareplicationandtranscription AT cristinasantamaria chromatinconformationregulatesthecoordinationbetweendnareplicationandtranscription AT jeancharlescadoret chromatinconformationregulatesthecoordinationbetweendnareplicationandtranscription AT lauracanoaroca chromatinconformationregulatesthecoordinationbetweendnareplicationandtranscription AT rodrigolombrana chromatinconformationregulatesthecoordinationbetweendnareplicationandtranscription AT gonzaloherranz chromatinconformationregulatesthecoordinationbetweendnareplicationandtranscription AT alessandraagresti chromatinconformationregulatesthecoordinationbetweendnareplicationandtranscription AT mariagomez chromatinconformationregulatesthecoordinationbetweendnareplicationandtranscription |
_version_ |
1718383092091060224 |