Chromatin conformation regulates the coordination between DNA replication and transcription

The maintenance of chromatin integrity during replication is critical for cell viability. Here the authors study how dividing cells respond to alterations in chromatin structure and find that these elicit a range of responses in the dynamics of DNA replication and consequences on replicative stress.

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Autores principales: Ricardo Almeida, José Miguel Fernández-Justel, Cristina Santa-María, Jean-Charles Cadoret, Laura Cano-Aroca, Rodrigo Lombraña, Gonzalo Herranz, Alessandra Agresti, María Gómez
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/399d7ceb0c43497db1da7ece90fc06c8
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spelling oai:doaj.org-article:399d7ceb0c43497db1da7ece90fc06c82021-12-02T16:50:10ZChromatin conformation regulates the coordination between DNA replication and transcription10.1038/s41467-018-03539-82041-1723https://doaj.org/article/399d7ceb0c43497db1da7ece90fc06c82018-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-03539-8https://doaj.org/toc/2041-1723The maintenance of chromatin integrity during replication is critical for cell viability. Here the authors study how dividing cells respond to alterations in chromatin structure and find that these elicit a range of responses in the dynamics of DNA replication and consequences on replicative stress.Ricardo AlmeidaJosé Miguel Fernández-JustelCristina Santa-MaríaJean-Charles CadoretLaura Cano-ArocaRodrigo LombrañaGonzalo HerranzAlessandra AgrestiMaría GómezNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Ricardo Almeida
José Miguel Fernández-Justel
Cristina Santa-María
Jean-Charles Cadoret
Laura Cano-Aroca
Rodrigo Lombraña
Gonzalo Herranz
Alessandra Agresti
María Gómez
Chromatin conformation regulates the coordination between DNA replication and transcription
description The maintenance of chromatin integrity during replication is critical for cell viability. Here the authors study how dividing cells respond to alterations in chromatin structure and find that these elicit a range of responses in the dynamics of DNA replication and consequences on replicative stress.
format article
author Ricardo Almeida
José Miguel Fernández-Justel
Cristina Santa-María
Jean-Charles Cadoret
Laura Cano-Aroca
Rodrigo Lombraña
Gonzalo Herranz
Alessandra Agresti
María Gómez
author_facet Ricardo Almeida
José Miguel Fernández-Justel
Cristina Santa-María
Jean-Charles Cadoret
Laura Cano-Aroca
Rodrigo Lombraña
Gonzalo Herranz
Alessandra Agresti
María Gómez
author_sort Ricardo Almeida
title Chromatin conformation regulates the coordination between DNA replication and transcription
title_short Chromatin conformation regulates the coordination between DNA replication and transcription
title_full Chromatin conformation regulates the coordination between DNA replication and transcription
title_fullStr Chromatin conformation regulates the coordination between DNA replication and transcription
title_full_unstemmed Chromatin conformation regulates the coordination between DNA replication and transcription
title_sort chromatin conformation regulates the coordination between dna replication and transcription
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/399d7ceb0c43497db1da7ece90fc06c8
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AT alessandraagresti chromatinconformationregulatesthecoordinationbetweendnareplicationandtranscription
AT mariagomez chromatinconformationregulatesthecoordinationbetweendnareplicationandtranscription
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