Alterations in promoter interaction landscape and transcriptional network underlying metabolic adaptation to diet

Metabolic adaptation to different diets results in changes to gene expression. Here, the authors characterise the chromatin landscape and transcriptional network in mice on a diet of high saturated fat, compared to a diet high in carbohydrate, finding a dramatic reprogramming of the liver transcript...

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Autores principales:	Yufeng Qin, Sara A. Grimm, John D. Roberts, Kaliopi Chrysovergis, Paul A. Wade
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/399f6a117f3b400fae52411f3fe2b896
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spelling	oai:doaj.org-article:399f6a117f3b400fae52411f3fe2b8962021-12-02T17:32:41ZAlterations in promoter interaction landscape and transcriptional network underlying metabolic adaptation to diet10.1038/s41467-020-14796-x2041-1723https://doaj.org/article/399f6a117f3b400fae52411f3fe2b8962020-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-14796-xhttps://doaj.org/toc/2041-1723Metabolic adaptation to different diets results in changes to gene expression. Here, the authors characterise the chromatin landscape and transcriptional network in mice on a diet of high saturated fat, compared to a diet high in carbohydrate, finding a dramatic reprogramming of the liver transcriptional network.Yufeng QinSara A. GrimmJohn D. RobertsKaliopi ChrysovergisPaul A. WadeNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Yufeng Qin Sara A. Grimm John D. Roberts Kaliopi Chrysovergis Paul A. Wade Alterations in promoter interaction landscape and transcriptional network underlying metabolic adaptation to diet
description	Metabolic adaptation to different diets results in changes to gene expression. Here, the authors characterise the chromatin landscape and transcriptional network in mice on a diet of high saturated fat, compared to a diet high in carbohydrate, finding a dramatic reprogramming of the liver transcriptional network.
format	article
author	Yufeng Qin Sara A. Grimm John D. Roberts Kaliopi Chrysovergis Paul A. Wade
author_facet	Yufeng Qin Sara A. Grimm John D. Roberts Kaliopi Chrysovergis Paul A. Wade
author_sort	Yufeng Qin
title	Alterations in promoter interaction landscape and transcriptional network underlying metabolic adaptation to diet
title_short	Alterations in promoter interaction landscape and transcriptional network underlying metabolic adaptation to diet
title_full	Alterations in promoter interaction landscape and transcriptional network underlying metabolic adaptation to diet
title_fullStr	Alterations in promoter interaction landscape and transcriptional network underlying metabolic adaptation to diet
title_full_unstemmed	Alterations in promoter interaction landscape and transcriptional network underlying metabolic adaptation to diet
title_sort	alterations in promoter interaction landscape and transcriptional network underlying metabolic adaptation to diet
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/399f6a117f3b400fae52411f3fe2b896
work_keys_str_mv	AT yufengqin alterationsinpromoterinteractionlandscapeandtranscriptionalnetworkunderlyingmetabolicadaptationtodiet AT saraagrimm alterationsinpromoterinteractionlandscapeandtranscriptionalnetworkunderlyingmetabolicadaptationtodiet AT johndroberts alterationsinpromoterinteractionlandscapeandtranscriptionalnetworkunderlyingmetabolicadaptationtodiet AT kaliopichrysovergis alterationsinpromoterinteractionlandscapeandtranscriptionalnetworkunderlyingmetabolicadaptationtodiet AT paulawade alterationsinpromoterinteractionlandscapeandtranscriptionalnetworkunderlyingmetabolicadaptationtodiet
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Alterations in promoter interaction landscape and transcriptional network underlying metabolic adaptation to diet

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