Role of Tim4 in the regulation of ABCA1+ adipose tissue macrophages and post-prandial cholesterol levels

Diverse macrophage subsets are found in adipose tissue where they regulate its physiology. Here, the authors used single-cell RNA sequencing to analyse the effect of post-prandial lipids on adipose tissue macrophages and identify Tim4 as a regulator of ABCA1+ macrophage function and post-prandial ch...

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Autores principales:	M. S. Magalhaes, P. Smith, J. R. Portman, L. H. Jackson-Jones, C. C. Bain, P. Ramachandran, Z. Michalidou, R. H. Stimson, M. R. Dweck, L. Denby, N. C. Henderson, S. J. Jenkins, C. Bénézech
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/39a4cc25e8ac438eaf00455de7457431
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spelling	oai:doaj.org-article:39a4cc25e8ac438eaf00455de74574312021-12-02T16:43:42ZRole of Tim4 in the regulation of ABCA1+ adipose tissue macrophages and post-prandial cholesterol levels10.1038/s41467-021-24684-72041-1723https://doaj.org/article/39a4cc25e8ac438eaf00455de74574312021-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-24684-7https://doaj.org/toc/2041-1723Diverse macrophage subsets are found in adipose tissue where they regulate its physiology. Here, the authors used single-cell RNA sequencing to analyse the effect of post-prandial lipids on adipose tissue macrophages and identify Tim4 as a regulator of ABCA1+ macrophage function and post-prandial cholesterol transport.M. S. MagalhaesP. SmithJ. R. PortmanL. H. Jackson-JonesC. C. BainP. RamachandranZ. MichalidouR. H. StimsonM. R. DweckL. DenbyN. C. HendersonS. J. JenkinsC. BénézechNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q M. S. Magalhaes P. Smith J. R. Portman L. H. Jackson-Jones C. C. Bain P. Ramachandran Z. Michalidou R. H. Stimson M. R. Dweck L. Denby N. C. Henderson S. J. Jenkins C. Bénézech Role of Tim4 in the regulation of ABCA1+ adipose tissue macrophages and post-prandial cholesterol levels
description	Diverse macrophage subsets are found in adipose tissue where they regulate its physiology. Here, the authors used single-cell RNA sequencing to analyse the effect of post-prandial lipids on adipose tissue macrophages and identify Tim4 as a regulator of ABCA1+ macrophage function and post-prandial cholesterol transport.
format	article
author	M. S. Magalhaes P. Smith J. R. Portman L. H. Jackson-Jones C. C. Bain P. Ramachandran Z. Michalidou R. H. Stimson M. R. Dweck L. Denby N. C. Henderson S. J. Jenkins C. Bénézech
author_facet	M. S. Magalhaes P. Smith J. R. Portman L. H. Jackson-Jones C. C. Bain P. Ramachandran Z. Michalidou R. H. Stimson M. R. Dweck L. Denby N. C. Henderson S. J. Jenkins C. Bénézech
author_sort	M. S. Magalhaes
title	Role of Tim4 in the regulation of ABCA1+ adipose tissue macrophages and post-prandial cholesterol levels
title_short	Role of Tim4 in the regulation of ABCA1+ adipose tissue macrophages and post-prandial cholesterol levels
title_full	Role of Tim4 in the regulation of ABCA1+ adipose tissue macrophages and post-prandial cholesterol levels
title_fullStr	Role of Tim4 in the regulation of ABCA1+ adipose tissue macrophages and post-prandial cholesterol levels
title_full_unstemmed	Role of Tim4 in the regulation of ABCA1+ adipose tissue macrophages and post-prandial cholesterol levels
title_sort	role of tim4 in the regulation of abca1+ adipose tissue macrophages and post-prandial cholesterol levels
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/39a4cc25e8ac438eaf00455de7457431
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Role of Tim4 in the regulation of ABCA1+ adipose tissue macrophages and post-prandial cholesterol levels

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