Neck circumference and waist circumference associated with cardiovascular events in type 2 diabetes (Beijing Community Diabetes Study 23)

Abstract Obesity increases the risk of developing cardiovascular disease and other metabolic diseases. We intended to compare three different anthropometric indicators of obesity, in predicting the incidence of cardiovascular events in Chinese type 2 diabetes. Beijing Community Diabetes Study was a...

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Autores principales:	Guang-Ran Yang, Ming-Xia Yuan, Gang Wan, Xue-Lian Zhang, Han-Jing Fu, Shen-Yuan Yuan, Liang-Xiang Zhu, Rong-Rong Xie, Jian-Dong Zhang, Yu-Ling Li, Yan-Hua Sun, Qin-Fang Dai, Da-Yong Gao, Xue-Li Cui, Jian-Qin Gao, Zi-Ming Wang, Ying-Jun Chen, Yong-Jin Li, Dong-Ming Hu, Juan Gao, Ying Gao, Jie Miao, Yu-Jie Chen, Rury. R. Holman
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/39a795378bb7455783cb3d58f797195c
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spelling	oai:doaj.org-article:39a795378bb7455783cb3d58f797195c2021-12-02T16:49:07ZNeck circumference and waist circumference associated with cardiovascular events in type 2 diabetes (Beijing Community Diabetes Study 23)10.1038/s41598-021-88927-92045-2322https://doaj.org/article/39a795378bb7455783cb3d58f797195c2021-05-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-88927-9https://doaj.org/toc/2045-2322Abstract Obesity increases the risk of developing cardiovascular disease and other metabolic diseases. We intended to compare three different anthropometric indicators of obesity, in predicting the incidence of cardiovascular events in Chinese type 2 diabetes. Beijing Community Diabetes Study was a prospective multi-center study conducted in Beijing community health centers. Type 2 diabetes patients from fourteen community health centers were enrolled at baseline. The primary endpoint was cardiovascular events. The upper quartile of neck circumference (NC) was set as greater NC. A total of 3299 diabetes patients were enrolled. In which, 941 (28.52%) had cardiovascular disease at baseline. Logistic analysis showed that central obesity (waist circumference (WC) above 90 cm in men and 85 cm in women) and greater NC were all related to baseline cardiovascular disease (adjusted OR = 1.49, and 1.55). After 10-year follow-up, 340 (10.31%) had cardiovascular events. Compared with patients without cardiovascular events, those having cardiovascular events had higher BMI, larger WC and NC. Cox regression analysis showed that greater WC and NC were all associated with the occurrence of cardiovascular events (adjusted HR = 1.41, and 1.38). A higher NC and WC might increase the risk of cardiovascular events by about 40% in type 2 diabetes patients in Beijing communities.Guang-Ran YangMing-Xia YuanGang WanXue-Lian ZhangHan-Jing FuShen-Yuan YuanLiang-Xiang ZhuRong-Rong XieJian-Dong ZhangYu-Ling LiYan-Hua SunQin-Fang DaiDa-Yong GaoXue-Li CuiJian-Qin GaoZi-Ming WangYing-Jun ChenYong-Jin LiDong-Ming HuJuan GaoYing GaoJie MiaoYu-Jie ChenRury. R. HolmanNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-7 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Guang-Ran Yang Ming-Xia Yuan Gang Wan Xue-Lian Zhang Han-Jing Fu Shen-Yuan Yuan Liang-Xiang Zhu Rong-Rong Xie Jian-Dong Zhang Yu-Ling Li Yan-Hua Sun Qin-Fang Dai Da-Yong Gao Xue-Li Cui Jian-Qin Gao Zi-Ming Wang Ying-Jun Chen Yong-Jin Li Dong-Ming Hu Juan Gao Ying Gao Jie Miao Yu-Jie Chen Rury. R. Holman Neck circumference and waist circumference associated with cardiovascular events in type 2 diabetes (Beijing Community Diabetes Study 23)
description	Abstract Obesity increases the risk of developing cardiovascular disease and other metabolic diseases. We intended to compare three different anthropometric indicators of obesity, in predicting the incidence of cardiovascular events in Chinese type 2 diabetes. Beijing Community Diabetes Study was a prospective multi-center study conducted in Beijing community health centers. Type 2 diabetes patients from fourteen community health centers were enrolled at baseline. The primary endpoint was cardiovascular events. The upper quartile of neck circumference (NC) was set as greater NC. A total of 3299 diabetes patients were enrolled. In which, 941 (28.52%) had cardiovascular disease at baseline. Logistic analysis showed that central obesity (waist circumference (WC) above 90 cm in men and 85 cm in women) and greater NC were all related to baseline cardiovascular disease (adjusted OR = 1.49, and 1.55). After 10-year follow-up, 340 (10.31%) had cardiovascular events. Compared with patients without cardiovascular events, those having cardiovascular events had higher BMI, larger WC and NC. Cox regression analysis showed that greater WC and NC were all associated with the occurrence of cardiovascular events (adjusted HR = 1.41, and 1.38). A higher NC and WC might increase the risk of cardiovascular events by about 40% in type 2 diabetes patients in Beijing communities.
format	article
author	Guang-Ran Yang Ming-Xia Yuan Gang Wan Xue-Lian Zhang Han-Jing Fu Shen-Yuan Yuan Liang-Xiang Zhu Rong-Rong Xie Jian-Dong Zhang Yu-Ling Li Yan-Hua Sun Qin-Fang Dai Da-Yong Gao Xue-Li Cui Jian-Qin Gao Zi-Ming Wang Ying-Jun Chen Yong-Jin Li Dong-Ming Hu Juan Gao Ying Gao Jie Miao Yu-Jie Chen Rury. R. Holman
author_facet	Guang-Ran Yang Ming-Xia Yuan Gang Wan Xue-Lian Zhang Han-Jing Fu Shen-Yuan Yuan Liang-Xiang Zhu Rong-Rong Xie Jian-Dong Zhang Yu-Ling Li Yan-Hua Sun Qin-Fang Dai Da-Yong Gao Xue-Li Cui Jian-Qin Gao Zi-Ming Wang Ying-Jun Chen Yong-Jin Li Dong-Ming Hu Juan Gao Ying Gao Jie Miao Yu-Jie Chen Rury. R. Holman
author_sort	Guang-Ran Yang
title	Neck circumference and waist circumference associated with cardiovascular events in type 2 diabetes (Beijing Community Diabetes Study 23)
title_short	Neck circumference and waist circumference associated with cardiovascular events in type 2 diabetes (Beijing Community Diabetes Study 23)
title_full	Neck circumference and waist circumference associated with cardiovascular events in type 2 diabetes (Beijing Community Diabetes Study 23)
title_fullStr	Neck circumference and waist circumference associated with cardiovascular events in type 2 diabetes (Beijing Community Diabetes Study 23)
title_full_unstemmed	Neck circumference and waist circumference associated with cardiovascular events in type 2 diabetes (Beijing Community Diabetes Study 23)
title_sort	neck circumference and waist circumference associated with cardiovascular events in type 2 diabetes (beijing community diabetes study 23)
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/39a795378bb7455783cb3d58f797195c
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Neck circumference and waist circumference associated with cardiovascular events in type 2 diabetes (Beijing Community Diabetes Study 23)

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