MOLECULAR-GENETIC BASIS OF PHYSIOLOGY AND PATHOGENICITY OF COXIELLA BURNETII

Abstract. The agent of Q-fever Coxiella burnetii is unusual intracellular pathogen which is possessed of biggest transporting and metabolic abilities in compare with microorganisms with similar parasitic strategy. It is supposed that different strains of the pathogen exist in various stages of patho...

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Autor principal:	Yu. A. Panpherova
Formato:	article
Lenguaje:	RU
Publicado:	Sankt-Peterburg : NIIÈM imeni Pastera 2014
Materias:	coxiella burnetii genome pathogenic adoption genomic groups genotyping Infectious and parasitic diseases RC109-216
Acceso en línea:	https://doaj.org/article/39aaefae793648efa9fb1c09a939f749
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spelling	oai:doaj.org-article:39aaefae793648efa9fb1c09a939f7492021-11-22T07:09:45ZMOLECULAR-GENETIC BASIS OF PHYSIOLOGY AND PATHOGENICITY OF COXIELLA BURNETII2220-76192313-739810.15789/2220-7619-2012-3-615-626https://doaj.org/article/39aaefae793648efa9fb1c09a939f7492014-07-01T00:00:00Zhttps://www.iimmun.ru/iimm/article/view/77https://doaj.org/toc/2220-7619https://doaj.org/toc/2313-7398Abstract. The agent of Q-fever Coxiella burnetii is unusual intracellular pathogen which is possessed of biggest transporting and metabolic abilities in compare with microorganisms with similar parasitic strategy. It is supposed that different strains of the pathogen exist in various stages of pathological adaption and have different potential of virulence. The structure of C. burnetii genome, characteristics of metabolic routes, mechanisms of interaction with host cells and possible virulence factors are discussed in the review. The special attention is paid to Coxiella genotyping methods and possible correlations between genomic polymorphism of different strains and their virulence potential.Yu. A. PanpherovaSankt-Peterburg : NIIÈM imeni Pasteraarticlecoxiella burnetiigenomepathogenic adoptiongenomic groupsgenotypingInfectious and parasitic diseasesRC109-216RUInfekciâ i Immunitet, Vol 2, Iss 3, Pp 615-626 (2014)
institution	DOAJ
collection	DOAJ
language	RU
topic	coxiella burnetii genome pathogenic adoption genomic groups genotyping Infectious and parasitic diseases RC109-216
spellingShingle	coxiella burnetii genome pathogenic adoption genomic groups genotyping Infectious and parasitic diseases RC109-216 Yu. A. Panpherova MOLECULAR-GENETIC BASIS OF PHYSIOLOGY AND PATHOGENICITY OF COXIELLA BURNETII
description	Abstract. The agent of Q-fever Coxiella burnetii is unusual intracellular pathogen which is possessed of biggest transporting and metabolic abilities in compare with microorganisms with similar parasitic strategy. It is supposed that different strains of the pathogen exist in various stages of pathological adaption and have different potential of virulence. The structure of C. burnetii genome, characteristics of metabolic routes, mechanisms of interaction with host cells and possible virulence factors are discussed in the review. The special attention is paid to Coxiella genotyping methods and possible correlations between genomic polymorphism of different strains and their virulence potential.
format	article
author	Yu. A. Panpherova
author_facet	Yu. A. Panpherova
author_sort	Yu. A. Panpherova
title	MOLECULAR-GENETIC BASIS OF PHYSIOLOGY AND PATHOGENICITY OF COXIELLA BURNETII
title_short	MOLECULAR-GENETIC BASIS OF PHYSIOLOGY AND PATHOGENICITY OF COXIELLA BURNETII
title_full	MOLECULAR-GENETIC BASIS OF PHYSIOLOGY AND PATHOGENICITY OF COXIELLA BURNETII
title_fullStr	MOLECULAR-GENETIC BASIS OF PHYSIOLOGY AND PATHOGENICITY OF COXIELLA BURNETII
title_full_unstemmed	MOLECULAR-GENETIC BASIS OF PHYSIOLOGY AND PATHOGENICITY OF COXIELLA BURNETII
title_sort	molecular-genetic basis of physiology and pathogenicity of coxiella burnetii
publisher	Sankt-Peterburg : NIIÈM imeni Pastera
publishDate	2014
url	https://doaj.org/article/39aaefae793648efa9fb1c09a939f749
work_keys_str_mv	AT yuapanpherova moleculargeneticbasisofphysiologyandpathogenicityofcoxiellaburnetii
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MOLECULAR-GENETIC BASIS OF PHYSIOLOGY AND PATHOGENICITY OF COXIELLA BURNETII

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