COMPARATIVE ANALYSIS OF COLON PREPARATION USING POLY ETHYLENE GLYCOL (PEG) WITH LACTULOSE FOR COLONOSCOPY

Objective: To compare the adequacy of preparation for colonoscopy using polyethylene glycol with lactulose. Study Design: Quasi experimental study. Place and Duration of Study: Department of Gastroenterology, Combined Military Hospital Lahore, from Jul 2019 to Dec 2019. Methodology: The enr...

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Autores principales: Asma Asghar, Laima Alam, Asif Farooq, Arshad Hayat, Farrukh Saeed, Jehangir Ahmed
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Lenguaje:EN
Publicado: Army Medical College Rawalpindi 2020
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Acceso en línea:https://doaj.org/article/39c2fba409e048c892c1471b2d93570b
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spelling oai:doaj.org-article:39c2fba409e048c892c1471b2d93570b2021-12-02T17:38:55ZCOMPARATIVE ANALYSIS OF COLON PREPARATION USING POLY ETHYLENE GLYCOL (PEG) WITH LACTULOSE FOR COLONOSCOPY0030-96482411-8842https://doaj.org/article/39c2fba409e048c892c1471b2d93570b2020-10-01T00:00:00Zhttps://pafmj.org/index.php/PAFMJ/article/view/5546https://doaj.org/toc/0030-9648https://doaj.org/toc/2411-8842Objective: To compare the adequacy of preparation for colonoscopy using polyethylene glycol with lactulose. Study Design: Quasi experimental study. Place and Duration of Study: Department of Gastroenterology, Combined Military Hospital Lahore, from Jul 2019 to Dec 2019. Methodology: The enrolled patients were randomized into two equal groups. Group A received polyethylene glycol (PEG) formulation containing 13.125g x 24 sachets with 4 liters of water over 24 hours, group B received lactulose 600ml (66.7g/100ml) with 4 liters of water over 24 hours. Quality of bowel preparation was assessed using Ottawa scoring system (OBPS). A designed questionnaire was used for recording patients’ tolerability toward the preparation method. Questionnaire was filled pre and post-procedure for socio-demographic data and scores. Patients were also assessed for tolerability of procedure and palatability of the solutions by questionnaire. Results: The median age of patients in group A was 49 (26 IQR) years and in group B was 48 (18.5 IQR) years. Out of 100 patients 60% were males and 40% were females. The most common indication of colonoscopy was anemia (32%), followed by diarrhea (26%), bleeding per-rectum (24%) and constipation (18%). Polyethylene glycol showed better bowel cleansing score compared with lactulose (p<0.001). Tolerability and palatability for polyethylene glycol were statistically superior to the same volume of lactulose. Conclusion: Polyethylene glycol is superior to lactulose in terms of bowel preparation, tolerability and palatability.Asma AsgharLaima AlamAsif FarooqArshad HayatFarrukh SaeedJehangir AhmedArmy Medical College Rawalpindiarticlebowel preparationcolonoscopylactuloseottawa scorepolyethylene glycol (peg)MedicineRMedicine (General)R5-920ENPakistan Armed Forces Medical Journal, Vol 70, Iss 5, Pp 1261-1265 (2020)
institution DOAJ
collection DOAJ
language EN
topic bowel preparation
colonoscopy
lactulose
ottawa score
polyethylene glycol (peg)
Medicine
R
Medicine (General)
R5-920
spellingShingle bowel preparation
colonoscopy
lactulose
ottawa score
polyethylene glycol (peg)
Medicine
R
Medicine (General)
R5-920
Asma Asghar
Laima Alam
Asif Farooq
Arshad Hayat
Farrukh Saeed
Jehangir Ahmed
COMPARATIVE ANALYSIS OF COLON PREPARATION USING POLY ETHYLENE GLYCOL (PEG) WITH LACTULOSE FOR COLONOSCOPY
description Objective: To compare the adequacy of preparation for colonoscopy using polyethylene glycol with lactulose. Study Design: Quasi experimental study. Place and Duration of Study: Department of Gastroenterology, Combined Military Hospital Lahore, from Jul 2019 to Dec 2019. Methodology: The enrolled patients were randomized into two equal groups. Group A received polyethylene glycol (PEG) formulation containing 13.125g x 24 sachets with 4 liters of water over 24 hours, group B received lactulose 600ml (66.7g/100ml) with 4 liters of water over 24 hours. Quality of bowel preparation was assessed using Ottawa scoring system (OBPS). A designed questionnaire was used for recording patients’ tolerability toward the preparation method. Questionnaire was filled pre and post-procedure for socio-demographic data and scores. Patients were also assessed for tolerability of procedure and palatability of the solutions by questionnaire. Results: The median age of patients in group A was 49 (26 IQR) years and in group B was 48 (18.5 IQR) years. Out of 100 patients 60% were males and 40% were females. The most common indication of colonoscopy was anemia (32%), followed by diarrhea (26%), bleeding per-rectum (24%) and constipation (18%). Polyethylene glycol showed better bowel cleansing score compared with lactulose (p<0.001). Tolerability and palatability for polyethylene glycol were statistically superior to the same volume of lactulose. Conclusion: Polyethylene glycol is superior to lactulose in terms of bowel preparation, tolerability and palatability.
format article
author Asma Asghar
Laima Alam
Asif Farooq
Arshad Hayat
Farrukh Saeed
Jehangir Ahmed
author_facet Asma Asghar
Laima Alam
Asif Farooq
Arshad Hayat
Farrukh Saeed
Jehangir Ahmed
author_sort Asma Asghar
title COMPARATIVE ANALYSIS OF COLON PREPARATION USING POLY ETHYLENE GLYCOL (PEG) WITH LACTULOSE FOR COLONOSCOPY
title_short COMPARATIVE ANALYSIS OF COLON PREPARATION USING POLY ETHYLENE GLYCOL (PEG) WITH LACTULOSE FOR COLONOSCOPY
title_full COMPARATIVE ANALYSIS OF COLON PREPARATION USING POLY ETHYLENE GLYCOL (PEG) WITH LACTULOSE FOR COLONOSCOPY
title_fullStr COMPARATIVE ANALYSIS OF COLON PREPARATION USING POLY ETHYLENE GLYCOL (PEG) WITH LACTULOSE FOR COLONOSCOPY
title_full_unstemmed COMPARATIVE ANALYSIS OF COLON PREPARATION USING POLY ETHYLENE GLYCOL (PEG) WITH LACTULOSE FOR COLONOSCOPY
title_sort comparative analysis of colon preparation using poly ethylene glycol (peg) with lactulose for colonoscopy
publisher Army Medical College Rawalpindi
publishDate 2020
url https://doaj.org/article/39c2fba409e048c892c1471b2d93570b
work_keys_str_mv AT asmaasghar comparativeanalysisofcolonpreparationusingpolyethyleneglycolpegwithlactuloseforcolonoscopy
AT laimaalam comparativeanalysisofcolonpreparationusingpolyethyleneglycolpegwithlactuloseforcolonoscopy
AT asiffarooq comparativeanalysisofcolonpreparationusingpolyethyleneglycolpegwithlactuloseforcolonoscopy
AT arshadhayat comparativeanalysisofcolonpreparationusingpolyethyleneglycolpegwithlactuloseforcolonoscopy
AT farrukhsaeed comparativeanalysisofcolonpreparationusingpolyethyleneglycolpegwithlactuloseforcolonoscopy
AT jehangirahmed comparativeanalysisofcolonpreparationusingpolyethyleneglycolpegwithlactuloseforcolonoscopy
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