COMPARATIVE ANALYSIS OF COLON PREPARATION USING POLY ETHYLENE GLYCOL (PEG) WITH LACTULOSE FOR COLONOSCOPY
Objective: To compare the adequacy of preparation for colonoscopy using polyethylene glycol with lactulose. Study Design: Quasi experimental study. Place and Duration of Study: Department of Gastroenterology, Combined Military Hospital Lahore, from Jul 2019 to Dec 2019. Methodology: The enr...
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Army Medical College Rawalpindi
2020
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oai:doaj.org-article:39c2fba409e048c892c1471b2d93570b2021-12-02T17:38:55ZCOMPARATIVE ANALYSIS OF COLON PREPARATION USING POLY ETHYLENE GLYCOL (PEG) WITH LACTULOSE FOR COLONOSCOPY0030-96482411-8842https://doaj.org/article/39c2fba409e048c892c1471b2d93570b2020-10-01T00:00:00Zhttps://pafmj.org/index.php/PAFMJ/article/view/5546https://doaj.org/toc/0030-9648https://doaj.org/toc/2411-8842Objective: To compare the adequacy of preparation for colonoscopy using polyethylene glycol with lactulose. Study Design: Quasi experimental study. Place and Duration of Study: Department of Gastroenterology, Combined Military Hospital Lahore, from Jul 2019 to Dec 2019. Methodology: The enrolled patients were randomized into two equal groups. Group A received polyethylene glycol (PEG) formulation containing 13.125g x 24 sachets with 4 liters of water over 24 hours, group B received lactulose 600ml (66.7g/100ml) with 4 liters of water over 24 hours. Quality of bowel preparation was assessed using Ottawa scoring system (OBPS). A designed questionnaire was used for recording patients’ tolerability toward the preparation method. Questionnaire was filled pre and post-procedure for socio-demographic data and scores. Patients were also assessed for tolerability of procedure and palatability of the solutions by questionnaire. Results: The median age of patients in group A was 49 (26 IQR) years and in group B was 48 (18.5 IQR) years. Out of 100 patients 60% were males and 40% were females. The most common indication of colonoscopy was anemia (32%), followed by diarrhea (26%), bleeding per-rectum (24%) and constipation (18%). Polyethylene glycol showed better bowel cleansing score compared with lactulose (p<0.001). Tolerability and palatability for polyethylene glycol were statistically superior to the same volume of lactulose. Conclusion: Polyethylene glycol is superior to lactulose in terms of bowel preparation, tolerability and palatability.Asma AsgharLaima AlamAsif FarooqArshad HayatFarrukh SaeedJehangir AhmedArmy Medical College Rawalpindiarticlebowel preparationcolonoscopylactuloseottawa scorepolyethylene glycol (peg)MedicineRMedicine (General)R5-920ENPakistan Armed Forces Medical Journal, Vol 70, Iss 5, Pp 1261-1265 (2020) |
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bowel preparation colonoscopy lactulose ottawa score polyethylene glycol (peg) Medicine R Medicine (General) R5-920 |
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bowel preparation colonoscopy lactulose ottawa score polyethylene glycol (peg) Medicine R Medicine (General) R5-920 Asma Asghar Laima Alam Asif Farooq Arshad Hayat Farrukh Saeed Jehangir Ahmed COMPARATIVE ANALYSIS OF COLON PREPARATION USING POLY ETHYLENE GLYCOL (PEG) WITH LACTULOSE FOR COLONOSCOPY |
description |
Objective: To compare the adequacy of preparation for colonoscopy using polyethylene glycol with lactulose.
Study Design: Quasi experimental study.
Place and Duration of Study: Department of Gastroenterology, Combined Military Hospital Lahore, from Jul 2019 to Dec 2019.
Methodology: The enrolled patients were randomized into two equal groups. Group A received polyethylene glycol (PEG) formulation containing 13.125g x 24 sachets with 4 liters of water over 24 hours, group B received lactulose 600ml (66.7g/100ml) with 4 liters of water over 24 hours. Quality of bowel preparation was assessed using Ottawa scoring system (OBPS). A designed questionnaire was used for recording patients’ tolerability toward the preparation method. Questionnaire was filled pre and post-procedure for socio-demographic data and scores. Patients were also assessed for tolerability of procedure and palatability of the solutions by questionnaire.
Results: The median age of patients in group A was 49 (26 IQR) years and in group B was 48 (18.5 IQR) years. Out of 100 patients 60% were males and 40% were females. The most common indication of colonoscopy was anemia (32%), followed by diarrhea (26%), bleeding per-rectum (24%) and constipation (18%). Polyethylene glycol showed better bowel cleansing score compared with lactulose (p<0.001). Tolerability and palatability for polyethylene glycol were statistically superior to the same volume of lactulose.
Conclusion: Polyethylene glycol is superior to lactulose in terms of bowel preparation, tolerability and palatability. |
format |
article |
author |
Asma Asghar Laima Alam Asif Farooq Arshad Hayat Farrukh Saeed Jehangir Ahmed |
author_facet |
Asma Asghar Laima Alam Asif Farooq Arshad Hayat Farrukh Saeed Jehangir Ahmed |
author_sort |
Asma Asghar |
title |
COMPARATIVE ANALYSIS OF COLON PREPARATION USING POLY ETHYLENE GLYCOL (PEG) WITH LACTULOSE FOR COLONOSCOPY |
title_short |
COMPARATIVE ANALYSIS OF COLON PREPARATION USING POLY ETHYLENE GLYCOL (PEG) WITH LACTULOSE FOR COLONOSCOPY |
title_full |
COMPARATIVE ANALYSIS OF COLON PREPARATION USING POLY ETHYLENE GLYCOL (PEG) WITH LACTULOSE FOR COLONOSCOPY |
title_fullStr |
COMPARATIVE ANALYSIS OF COLON PREPARATION USING POLY ETHYLENE GLYCOL (PEG) WITH LACTULOSE FOR COLONOSCOPY |
title_full_unstemmed |
COMPARATIVE ANALYSIS OF COLON PREPARATION USING POLY ETHYLENE GLYCOL (PEG) WITH LACTULOSE FOR COLONOSCOPY |
title_sort |
comparative analysis of colon preparation using poly ethylene glycol (peg) with lactulose for colonoscopy |
publisher |
Army Medical College Rawalpindi |
publishDate |
2020 |
url |
https://doaj.org/article/39c2fba409e048c892c1471b2d93570b |
work_keys_str_mv |
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1718379815948517376 |