Distribution of microRNA profiles in pre-clinical and clinical forms of murine and human prion disease

Cheng et al. present differentially expressed extracellular vesicle miRNAs in human clinical samples from patients who suffer from sporadic Creutzfeldt-Jakob disease. This study identifies biomarkers that can be used to detect prion-related diseases, providing insights into drug development for inhi...

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Autores principales:	Lesley Cheng, Camelia Quek, Xia Li, Shayne A. Bellingham, Laura J. Ellett, Mitch Shambrook, Saima Zafar, Inga Zerr, Victoria A. Lawson, Andrew F. Hill
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/39c8cfc317f54c2eb8c47b3a23e018f6
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spelling	oai:doaj.org-article:39c8cfc317f54c2eb8c47b3a23e018f62021-12-02T11:45:00ZDistribution of microRNA profiles in pre-clinical and clinical forms of murine and human prion disease10.1038/s42003-021-01868-x2399-3642https://doaj.org/article/39c8cfc317f54c2eb8c47b3a23e018f62021-03-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-01868-xhttps://doaj.org/toc/2399-3642Cheng et al. present differentially expressed extracellular vesicle miRNAs in human clinical samples from patients who suffer from sporadic Creutzfeldt-Jakob disease. This study identifies biomarkers that can be used to detect prion-related diseases, providing insights into drug development for inhibiting prion infectivity.Lesley ChengCamelia QuekXia LiShayne A. BellinghamLaura J. EllettMitch ShambrookSaima ZafarInga ZerrVictoria A. LawsonAndrew F. HillNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-12 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Biology (General) QH301-705.5
spellingShingle	Biology (General) QH301-705.5 Lesley Cheng Camelia Quek Xia Li Shayne A. Bellingham Laura J. Ellett Mitch Shambrook Saima Zafar Inga Zerr Victoria A. Lawson Andrew F. Hill Distribution of microRNA profiles in pre-clinical and clinical forms of murine and human prion disease
description	Cheng et al. present differentially expressed extracellular vesicle miRNAs in human clinical samples from patients who suffer from sporadic Creutzfeldt-Jakob disease. This study identifies biomarkers that can be used to detect prion-related diseases, providing insights into drug development for inhibiting prion infectivity.
format	article
author	Lesley Cheng Camelia Quek Xia Li Shayne A. Bellingham Laura J. Ellett Mitch Shambrook Saima Zafar Inga Zerr Victoria A. Lawson Andrew F. Hill
author_facet	Lesley Cheng Camelia Quek Xia Li Shayne A. Bellingham Laura J. Ellett Mitch Shambrook Saima Zafar Inga Zerr Victoria A. Lawson Andrew F. Hill
author_sort	Lesley Cheng
title	Distribution of microRNA profiles in pre-clinical and clinical forms of murine and human prion disease
title_short	Distribution of microRNA profiles in pre-clinical and clinical forms of murine and human prion disease
title_full	Distribution of microRNA profiles in pre-clinical and clinical forms of murine and human prion disease
title_fullStr	Distribution of microRNA profiles in pre-clinical and clinical forms of murine and human prion disease
title_full_unstemmed	Distribution of microRNA profiles in pre-clinical and clinical forms of murine and human prion disease
title_sort	distribution of microrna profiles in pre-clinical and clinical forms of murine and human prion disease
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/39c8cfc317f54c2eb8c47b3a23e018f6
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Distribution of microRNA profiles in pre-clinical and clinical forms of murine and human prion disease

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