Inflammation, insulin resistance, and diabetes--Mendelian randomization using CRP haplotypes points upstream.

<h4>Background</h4>Raised C-reactive protein (CRP) is a risk factor for type 2 diabetes. According to the Mendelian randomization method, the association is likely to be causal if genetic variants that affect CRP level are associated with markers of diabetes development and diabetes. Our...

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Auteurs principaux:	Eric J Brunner, Mika Kivimäki, Daniel R Witte, Debbie A Lawlor, George Davey Smith, Jackie A Cooper, Michelle Miller, Gordon D O Lowe, Ann Rumley, Juan P Casas, Tina Shah, Steve E Humphries, Aroon D Hingorani, Michael G Marmot, Nicholas J Timpson, Meena Kumari
Format:	article
Langue:	EN
Publié:	Public Library of Science (PLoS) 2008
Sujets:	Medicine R
Accès en ligne:	https://doaj.org/article/39cef5eb7a05484caf34342a337e04d6
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Inflammation, insulin resistance, and diabetes--Mendelian randomization using CRP haplotypes points upstream.

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