Decreased long-chain acylcarnitines from insufficient β-oxidation as potential early diagnostic markers for Parkinson’s disease

Decreased long-chain acylcarnitines from insufficient β-oxidation as potential early diagnostic markers for Parkinson’s disease

Abstract Increasing evidence shows that metabolic abnormalities in body fluids are distinguishing features of the pathophysiology of Parkinson’s disease. However, a non-invasive approach has not been established in the earliest or pre-symptomatic phases. Here, we report comprehensive double-cohort a...

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Main Authors: Shinji Saiki, Taku Hatano, Motoki Fujimaki, Kei-Ichi Ishikawa, Akio Mori, Yutaka Oji, Ayami Okuzumi, Takeshi Fukuhara, Takahiro Koinuma, Yoko Imamichi, Miho Nagumo, Norihiko Furuya, Shuko Nojiri, Taku Amo, Kazuo Yamashiro, Nobutaka Hattori
Format: article
Language:EN
Published: Nature Portfolio 2017
Subjects:
Medicine
R
Science
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Online Access:https://doaj.org/article/39cf9e83253748d8b72eb80e81610158
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https://doaj.org/article/39cf9e83253748d8b72eb80e81610158

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