A neural m6A/Ythdf pathway is required for learning and memory in Drosophila

Epitranscriptomic modifications can regulate learning and memory. Here, the authors provide proteomic and functional analysis of N6-methyladenosine (m6A)-binding proteins in D. melanogaster and unveil behavioral and regulatory defects for m6A/Ythdf mutants.

Guardado en:

Detalles Bibliográficos
Autores principales:	Lijuan Kan, Stanislav Ott, Brian Joseph, Eun Sil Park, Wei Dai, Ralph E. Kleiner, Adam Claridge-Chang, Eric C. Lai
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/39d140120489475e99f3279baf323698
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:39d140120489475e99f3279baf323698
record_format	dspace
spelling	oai:doaj.org-article:39d140120489475e99f3279baf3236982021-12-02T15:52:37ZA neural m6A/Ythdf pathway is required for learning and memory in Drosophila10.1038/s41467-021-21537-12041-1723https://doaj.org/article/39d140120489475e99f3279baf3236982021-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-21537-1https://doaj.org/toc/2041-1723Epitranscriptomic modifications can regulate learning and memory. Here, the authors provide proteomic and functional analysis of N6-methyladenosine (m6A)-binding proteins in D. melanogaster and unveil behavioral and regulatory defects for m6A/Ythdf mutants.Lijuan KanStanislav OttBrian JosephEun Sil ParkWei DaiRalph E. KleinerAdam Claridge-ChangEric C. LaiNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Lijuan Kan Stanislav Ott Brian Joseph Eun Sil Park Wei Dai Ralph E. Kleiner Adam Claridge-Chang Eric C. Lai A neural m6A/Ythdf pathway is required for learning and memory in Drosophila
description	Epitranscriptomic modifications can regulate learning and memory. Here, the authors provide proteomic and functional analysis of N6-methyladenosine (m6A)-binding proteins in D. melanogaster and unveil behavioral and regulatory defects for m6A/Ythdf mutants.
format	article
author	Lijuan Kan Stanislav Ott Brian Joseph Eun Sil Park Wei Dai Ralph E. Kleiner Adam Claridge-Chang Eric C. Lai
author_facet	Lijuan Kan Stanislav Ott Brian Joseph Eun Sil Park Wei Dai Ralph E. Kleiner Adam Claridge-Chang Eric C. Lai
author_sort	Lijuan Kan
title	A neural m6A/Ythdf pathway is required for learning and memory in Drosophila
title_short	A neural m6A/Ythdf pathway is required for learning and memory in Drosophila
title_full	A neural m6A/Ythdf pathway is required for learning and memory in Drosophila
title_fullStr	A neural m6A/Ythdf pathway is required for learning and memory in Drosophila
title_full_unstemmed	A neural m6A/Ythdf pathway is required for learning and memory in Drosophila
title_sort	neural m6a/ythdf pathway is required for learning and memory in drosophila
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/39d140120489475e99f3279baf323698
work_keys_str_mv	AT lijuankan aneuralm6aythdfpathwayisrequiredforlearningandmemoryindrosophila AT stanislavott aneuralm6aythdfpathwayisrequiredforlearningandmemoryindrosophila AT brianjoseph aneuralm6aythdfpathwayisrequiredforlearningandmemoryindrosophila AT eunsilpark aneuralm6aythdfpathwayisrequiredforlearningandmemoryindrosophila AT weidai aneuralm6aythdfpathwayisrequiredforlearningandmemoryindrosophila AT ralphekleiner aneuralm6aythdfpathwayisrequiredforlearningandmemoryindrosophila AT adamclaridgechang aneuralm6aythdfpathwayisrequiredforlearningandmemoryindrosophila AT ericclai aneuralm6aythdfpathwayisrequiredforlearningandmemoryindrosophila AT lijuankan neuralm6aythdfpathwayisrequiredforlearningandmemoryindrosophila AT stanislavott neuralm6aythdfpathwayisrequiredforlearningandmemoryindrosophila AT brianjoseph neuralm6aythdfpathwayisrequiredforlearningandmemoryindrosophila AT eunsilpark neuralm6aythdfpathwayisrequiredforlearningandmemoryindrosophila AT weidai neuralm6aythdfpathwayisrequiredforlearningandmemoryindrosophila AT ralphekleiner neuralm6aythdfpathwayisrequiredforlearningandmemoryindrosophila AT adamclaridgechang neuralm6aythdfpathwayisrequiredforlearningandmemoryindrosophila AT ericclai neuralm6aythdfpathwayisrequiredforlearningandmemoryindrosophila
_version_	1718385563922333696

A neural m6A/Ythdf pathway is required for learning and memory in Drosophila

Ejemplares similares