Genome-wide RNA polymerase II profiles and RNA accumulation reveal kinetics of transcription and associated epigenetic changes during diurnal cycles.

Genome-wide RNA polymerase II profiles and RNA accumulation reveal kinetics of transcription and associated epigenetic changes during diurnal cycles.

Interactions of cell-autonomous circadian oscillators with diurnal cycles govern the temporal compartmentalization of cell physiology in mammals. To understand the transcriptional and epigenetic basis of diurnal rhythms in mouse liver genome-wide, we generated temporal DNA occupancy profiles by RNA...

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Detalles Bibliográficos
Autores principales: Gwendal Le Martelot, Donatella Canella, Laura Symul, Eugenia Migliavacca, Federica Gilardi, Robin Liechti, Olivier Martin, Keith Harshman, Mauro Delorenzi, Béatrice Desvergne, Winship Herr, Bart Deplancke, Ueli Schibler, Jacques Rougemont, Nicolas Guex, Nouria Hernandez, Felix Naef, CycliX Consortium
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
Materias:
Biology (General)
QH301-705.5
Acceso en línea:https://doaj.org/article/39ea2125b291414090a9397d877a0053
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https://doaj.org/article/39ea2125b291414090a9397d877a0053

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