Characteristics of the type 2 diabetic patients with hypoglycemia in a tertiary referral hospital

Background. Hypoglycemia is an important complication of the treatment of type 2 diabetes mellitus, which constitutes a barrier in stringent diabetic control. Beside it constitutes nearly 10 % of emergency department admissions that caused by adverse drug events, it may also increase morbidities and...

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Autores principales: Satilmis Bilgin, Gulali Aktas, Ozge Kurtkulagi, Burcin M. Atak, Gizem Kahveci, Muhammed E. Demirkol, Tuba T. Duman
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Publicado: Publishing House Zaslavsky 2021
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spelling oai:doaj.org-article:39f67e6809464a0d826603918f6f0e3c2021-11-22T11:26:20ZCharacteristics of the type 2 diabetic patients with hypoglycemia in a tertiary referral hospital2224-07212307-142710.22141/2224-0721.17.6.2021.243209https://doaj.org/article/39f67e6809464a0d826603918f6f0e3c2021-10-01T00:00:00Zhttp://iej.zaslavsky.com.ua/article/view/243209https://doaj.org/toc/2224-0721https://doaj.org/toc/2307-1427Background. Hypoglycemia is an important complication of the treatment of type 2 diabetes mellitus, which constitutes a barrier in stringent diabetic control. Beside it constitutes nearly 10 % of emergency department admissions that caused by adverse drug events, it may also increase morbidities and mortality by inducing, cardiac arrhythmias, neurological impairment and ischemic events. Hypoglycemia is the most common side effect of insulin treatment, however, oral antidiabetic agents may also induce hypoglycemic complications. In present retrospective study, we purposed to observe general characteristics and laboratory data of the type 2 diabetic patients whom presented with mild or moderate/severe hypoglycemia. Materials and methods. Patients with type 2 diabetes mellitus whom presented to our institution with hypoglycemia between January 2019 and January 2020 were retrospectively analyzed. General characteristics and laboratory data of the subjects recorded. Patients grouped into two groups, group I consisted of subjects with mild hypoglycemia and group II consisted of patients with moderate/severe hypoglycemia. Data of the subjects in groups I and II were compared. Results. There were 15 subjects in group I and 23 in group II. HbA1c and other laboratory markers were not significantly different in study groups. Similarly diabetes duration and anti-diabetic treatment were not significantly different in study groups. The rate of geriatric patients was significantly higher in group II compared to group I (p = 0.04). Conclusions. Subjects with moderate/severe hypoglycemia tend to be more frequently in geriatric age and HbA1c not correlates with the degree of the hypoglycemia. Since neither duration of diabetes, nor anti-diabetic treatment were associated with the severity of the hypoglycemia, each case should be evaluated individually to prevent further episodes which could increase morbidity and mortality in diabetic population.Satilmis BilginGulali AktasOzge KurtkulagiBurcin M. AtakGizem KahveciMuhammed E. DemirkolTuba T. DumanPublishing House Zaslavskyarticlehypoglycemia, type 2 diabetes mellitus, glycated hemoglobinDiseases of the endocrine glands. Clinical endocrinologyRC648-665ENRUUKMìžnarodnij Endokrinologìčnij Žurnal, Vol 17, Iss 6, Pp 472-476 (2021)
institution DOAJ
collection DOAJ
language EN
RU
UK
topic hypoglycemia, type 2 diabetes mellitus, glycated hemoglobin
Diseases of the endocrine glands. Clinical endocrinology
RC648-665
spellingShingle hypoglycemia, type 2 diabetes mellitus, glycated hemoglobin
Diseases of the endocrine glands. Clinical endocrinology
RC648-665
Satilmis Bilgin
Gulali Aktas
Ozge Kurtkulagi
Burcin M. Atak
Gizem Kahveci
Muhammed E. Demirkol
Tuba T. Duman
Characteristics of the type 2 diabetic patients with hypoglycemia in a tertiary referral hospital
description Background. Hypoglycemia is an important complication of the treatment of type 2 diabetes mellitus, which constitutes a barrier in stringent diabetic control. Beside it constitutes nearly 10 % of emergency department admissions that caused by adverse drug events, it may also increase morbidities and mortality by inducing, cardiac arrhythmias, neurological impairment and ischemic events. Hypoglycemia is the most common side effect of insulin treatment, however, oral antidiabetic agents may also induce hypoglycemic complications. In present retrospective study, we purposed to observe general characteristics and laboratory data of the type 2 diabetic patients whom presented with mild or moderate/severe hypoglycemia. Materials and methods. Patients with type 2 diabetes mellitus whom presented to our institution with hypoglycemia between January 2019 and January 2020 were retrospectively analyzed. General characteristics and laboratory data of the subjects recorded. Patients grouped into two groups, group I consisted of subjects with mild hypoglycemia and group II consisted of patients with moderate/severe hypoglycemia. Data of the subjects in groups I and II were compared. Results. There were 15 subjects in group I and 23 in group II. HbA1c and other laboratory markers were not significantly different in study groups. Similarly diabetes duration and anti-diabetic treatment were not significantly different in study groups. The rate of geriatric patients was significantly higher in group II compared to group I (p = 0.04). Conclusions. Subjects with moderate/severe hypoglycemia tend to be more frequently in geriatric age and HbA1c not correlates with the degree of the hypoglycemia. Since neither duration of diabetes, nor anti-diabetic treatment were associated with the severity of the hypoglycemia, each case should be evaluated individually to prevent further episodes which could increase morbidity and mortality in diabetic population.
format article
author Satilmis Bilgin
Gulali Aktas
Ozge Kurtkulagi
Burcin M. Atak
Gizem Kahveci
Muhammed E. Demirkol
Tuba T. Duman
author_facet Satilmis Bilgin
Gulali Aktas
Ozge Kurtkulagi
Burcin M. Atak
Gizem Kahveci
Muhammed E. Demirkol
Tuba T. Duman
author_sort Satilmis Bilgin
title Characteristics of the type 2 diabetic patients with hypoglycemia in a tertiary referral hospital
title_short Characteristics of the type 2 diabetic patients with hypoglycemia in a tertiary referral hospital
title_full Characteristics of the type 2 diabetic patients with hypoglycemia in a tertiary referral hospital
title_fullStr Characteristics of the type 2 diabetic patients with hypoglycemia in a tertiary referral hospital
title_full_unstemmed Characteristics of the type 2 diabetic patients with hypoglycemia in a tertiary referral hospital
title_sort characteristics of the type 2 diabetic patients with hypoglycemia in a tertiary referral hospital
publisher Publishing House Zaslavsky
publishDate 2021
url https://doaj.org/article/39f67e6809464a0d826603918f6f0e3c
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