STAG2 deficiency induces interferon responses via cGAS-STING pathway and restricts virus infection
Cohesin is a multimeric nuclear protein complex which includes STAG2 and is associated with vital roles during cell division. Here in a genome-wide CRISPR-Cas9 screen, the authors identify a novel role of STAG2 as a crucial component of the innate immune response to rotavirus.
Enregistré dans:
| Auteurs principaux: | , , , , , , , , , , , , , |
|---|---|
| Format: | article |
| Langue: | EN |
| Publié: |
Nature Portfolio
2018
|
| Sujets: | |
| Accès en ligne: | https://doaj.org/article/3a027c89acd64fe3a34c3ec69ad04b0a |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|
Soyez le premier à ajouter un commentaire!