Identification of flux checkpoints in a metabolic pathway through white-box, grey-box and black-box modeling approaches

Abstract Metabolic pathway modeling plays an increasing role in drug design by allowing better understanding of the underlying regulation and controlling networks in the metabolism of living organisms. However, despite rapid progress in this area, pathway modeling can become a real nightmare for res...

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Auteurs principaux: Ophélie Lo-Thong, Philippe Charton, Xavier F. Cadet, Brigitte Grondin-Perez, Emma Saavedra, Cédric Damour, Frédéric Cadet
Format: article
Langue:EN
Publié: Nature Portfolio 2020
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Accès en ligne:https://doaj.org/article/3a136d7e4cb74fb8882a1b9f52cfe5f0
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