Role of adipose tissue in facial aging

Uwe Wollina,1 Reinhard Wetzker,2 Mohamed Badawy Abdel-Naser,3 Ilja L Kruglikov4 1Department of Dermatology and Allergology, Academic Teaching Hospital Dresden-Friedrichstadt, Dresden, 2Department of Anesthesiology and Intensive Care Medicine, and Center for Sepsis Control and Care, Jena University...

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Auteurs principaux:	Wollina U, Wetzker R, Abdel-Naser MB, Kruglikov IL
Format:	article
Langue:	EN
Publié:	Dove Medical Press 2017
Sujets:	Facial aging adipose tissue preadipocytes adipocytes inflammation beiging adipocyte-myofibroblast transition Geriatrics RC952-954.6
Accès en ligne:	https://doaj.org/article/3a19588bedd043d58f00663df05d6e1b
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spelling	oai:doaj.org-article:3a19588bedd043d58f00663df05d6e1b2021-12-02T05:58:06ZRole of adipose tissue in facial aging1178-1998https://doaj.org/article/3a19588bedd043d58f00663df05d6e1b2017-12-01T00:00:00Zhttps://www.dovepress.com/role-of-adipose-tissue-in-facial-aging-peer-reviewed-article-CIAhttps://doaj.org/toc/1178-1998Uwe Wollina,1 Reinhard Wetzker,2 Mohamed Badawy Abdel-Naser,3 Ilja L Kruglikov4 1Department of Dermatology and Allergology, Academic Teaching Hospital Dresden-Friedrichstadt, Dresden, 2Department of Anesthesiology and Intensive Care Medicine, and Center for Sepsis Control and Care, Jena University Hospital, Jena, Germany; 3Department of Dermatology and Venereology, Ain Shams University Hospital, Cairo, Egypt; 4Wellcomet GmbH, Karlsruhe, Germany Abstract: Age-dependent modification of the facial subcutaneous white adipose tissue (sWAT) connected with reduction of its volume, modification of collagen content and adhesion between dermal and adipose layers can significantly influence mechanical stability of the skin and cause the development of aging symptoms such as wrinkles. Typical aging appearance in facial skin is at least partly connected with special phenotypical features of facial preadipocytes and mature adipocytes. In this paper, we have discussed the possible roles of local inflammation, compartmental structure of facial sWAT and trans-differentiation processes such as beiging of white adipocytes and adipocyte-myofibroblast transition in facial skin aging. Keywords: facial aging, adipose tissue, preadipocytes, adipocytes, inflammation, beiging, adipocyte-myofibroblast transition Wollina UWetzker RAbdel-Naser MBKruglikov ILDove Medical PressarticleFacial agingadipose tissuepreadipocytesadipocytesinflammationbeigingadipocyte-myofibroblast transitionGeriatricsRC952-954.6ENClinical Interventions in Aging, Vol Volume 12, Pp 2069-2076 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Facial aging adipose tissue preadipocytes adipocytes inflammation beiging adipocyte-myofibroblast transition Geriatrics RC952-954.6
spellingShingle	Facial aging adipose tissue preadipocytes adipocytes inflammation beiging adipocyte-myofibroblast transition Geriatrics RC952-954.6 Wollina U Wetzker R Abdel-Naser MB Kruglikov IL Role of adipose tissue in facial aging
description	Uwe Wollina,1 Reinhard Wetzker,2 Mohamed Badawy Abdel-Naser,3 Ilja L Kruglikov4 1Department of Dermatology and Allergology, Academic Teaching Hospital Dresden-Friedrichstadt, Dresden, 2Department of Anesthesiology and Intensive Care Medicine, and Center for Sepsis Control and Care, Jena University Hospital, Jena, Germany; 3Department of Dermatology and Venereology, Ain Shams University Hospital, Cairo, Egypt; 4Wellcomet GmbH, Karlsruhe, Germany Abstract: Age-dependent modification of the facial subcutaneous white adipose tissue (sWAT) connected with reduction of its volume, modification of collagen content and adhesion between dermal and adipose layers can significantly influence mechanical stability of the skin and cause the development of aging symptoms such as wrinkles. Typical aging appearance in facial skin is at least partly connected with special phenotypical features of facial preadipocytes and mature adipocytes. In this paper, we have discussed the possible roles of local inflammation, compartmental structure of facial sWAT and trans-differentiation processes such as beiging of white adipocytes and adipocyte-myofibroblast transition in facial skin aging. Keywords: facial aging, adipose tissue, preadipocytes, adipocytes, inflammation, beiging, adipocyte-myofibroblast transition
format	article
author	Wollina U Wetzker R Abdel-Naser MB Kruglikov IL
author_facet	Wollina U Wetzker R Abdel-Naser MB Kruglikov IL
author_sort	Wollina U
title	Role of adipose tissue in facial aging
title_short	Role of adipose tissue in facial aging
title_full	Role of adipose tissue in facial aging
title_fullStr	Role of adipose tissue in facial aging
title_full_unstemmed	Role of adipose tissue in facial aging
title_sort	role of adipose tissue in facial aging
publisher	Dove Medical Press
publishDate	2017
url	https://doaj.org/article/3a19588bedd043d58f00663df05d6e1b
work_keys_str_mv	AT wollinau roleofadiposetissueinfacialaging AT wetzkerr roleofadiposetissueinfacialaging AT abdelnasermb roleofadiposetissueinfacialaging AT kruglikovil roleofadiposetissueinfacialaging
_version_	1718400103323009024

Role of adipose tissue in facial aging

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