Systematic functional analysis of kinases in the fungal pathogen Cryptococcus neoformans

Systematic functional analysis of kinases in the fungal pathogen Cryptococcus neoformans

Cryptococcus neoformans is the leading cause of death by fungal meningoencephalitis. Here, the authors study the roles played by 129 putative kinases in the growth and virulence of C. neoformans, identifying potential targets for development of anticryptococcal drugs.

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Autores principales: Kyung-Tae Lee, Yee-Seul So, Dong-Hoon Yang, Kwang-Woo Jung, Jaeyoung Choi, Dong-Gi Lee, Hyojeong Kwon, Juyeong Jang, Li Li Wang, Soohyun Cha, Gena Lee Meyers, Eunji Jeong, Jae-Hyung Jin, Yeonseon Lee, Joohyeon Hong, Soohyun Bang, Je-Hyun Ji, Goun Park, Hyo-Jeong Byun, Sung Woo Park, Young-Min Park, Gloria Adedoyin, Taeyup Kim, Anna F. Averette, Jong-Soon Choi, Joseph Heitman, Eunji Cheong, Yong-Hwan Lee, Yong-Sun Bahn
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Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/3a1ac90e57ee4c81b3111fca0a130680
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spelling oai:doaj.org-article:3a1ac90e57ee4c81b3111fca0a1306802021-12-02T15:34:09ZSystematic functional analysis of kinases in the fungal pathogen Cryptococcus neoformans10.1038/ncomms127662041-1723https://doaj.org/article/3a1ac90e57ee4c81b3111fca0a1306802016-09-01T00:00:00Zhttps://doi.org/10.1038/ncomms12766https://doaj.org/toc/2041-1723Cryptococcus neoformans is the leading cause of death by fungal meningoencephalitis. Here, the authors study the roles played by 129 putative kinases in the growth and virulence of C. neoformans, identifying potential targets for development of anticryptococcal drugs.Kyung-Tae LeeYee-Seul SoDong-Hoon YangKwang-Woo JungJaeyoung ChoiDong-Gi LeeHyojeong KwonJuyeong JangLi Li WangSoohyun ChaGena Lee MeyersEunji JeongJae-Hyung JinYeonseon LeeJoohyeon HongSoohyun BangJe-Hyun JiGoun ParkHyo-Jeong ByunSung Woo ParkYoung-Min ParkGloria AdedoyinTaeyup KimAnna F. AveretteJong-Soon ChoiJoseph HeitmanEunji CheongYong-Hwan LeeYong-Sun BahnNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-16 (2016)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Kyung-Tae Lee
Yee-Seul So
Dong-Hoon Yang
Kwang-Woo Jung
Jaeyoung Choi
Dong-Gi Lee
Hyojeong Kwon
Juyeong Jang
Li Li Wang
Soohyun Cha
Gena Lee Meyers
Eunji Jeong
Jae-Hyung Jin
Yeonseon Lee
Joohyeon Hong
Soohyun Bang
Je-Hyun Ji
Goun Park
Hyo-Jeong Byun
Sung Woo Park
Young-Min Park
Gloria Adedoyin
Taeyup Kim
Anna F. Averette
Jong-Soon Choi
Joseph Heitman
Eunji Cheong
Yong-Hwan Lee
Yong-Sun Bahn
Systematic functional analysis of kinases in the fungal pathogen Cryptococcus neoformans
description Cryptococcus neoformans is the leading cause of death by fungal meningoencephalitis. Here, the authors study the roles played by 129 putative kinases in the growth and virulence of C. neoformans, identifying potential targets for development of anticryptococcal drugs.
format article
author Kyung-Tae Lee
Yee-Seul So
Dong-Hoon Yang
Kwang-Woo Jung
Jaeyoung Choi
Dong-Gi Lee
Hyojeong Kwon
Juyeong Jang
Li Li Wang
Soohyun Cha
Gena Lee Meyers
Eunji Jeong
Jae-Hyung Jin
Yeonseon Lee
Joohyeon Hong
Soohyun Bang
Je-Hyun Ji
Goun Park
Hyo-Jeong Byun
Sung Woo Park
Young-Min Park
Gloria Adedoyin
Taeyup Kim
Anna F. Averette
Jong-Soon Choi
Joseph Heitman
Eunji Cheong
Yong-Hwan Lee
Yong-Sun Bahn
author_facet Kyung-Tae Lee
Yee-Seul So
Dong-Hoon Yang
Kwang-Woo Jung
Jaeyoung Choi
Dong-Gi Lee
Hyojeong Kwon
Juyeong Jang
Li Li Wang
Soohyun Cha
Gena Lee Meyers
Eunji Jeong
Jae-Hyung Jin
Yeonseon Lee
Joohyeon Hong
Soohyun Bang
Je-Hyun Ji
Goun Park
Hyo-Jeong Byun
Sung Woo Park
Young-Min Park
Gloria Adedoyin
Taeyup Kim
Anna F. Averette
Jong-Soon Choi
Joseph Heitman
Eunji Cheong
Yong-Hwan Lee
Yong-Sun Bahn
author_sort Kyung-Tae Lee
title Systematic functional analysis of kinases in the fungal pathogen Cryptococcus neoformans
title_short Systematic functional analysis of kinases in the fungal pathogen Cryptococcus neoformans
title_full Systematic functional analysis of kinases in the fungal pathogen Cryptococcus neoformans
title_fullStr Systematic functional analysis of kinases in the fungal pathogen Cryptococcus neoformans
title_full_unstemmed Systematic functional analysis of kinases in the fungal pathogen Cryptococcus neoformans
title_sort systematic functional analysis of kinases in the fungal pathogen cryptococcus neoformans
publisher Nature Portfolio
publishDate 2016
url https://doaj.org/article/3a1ac90e57ee4c81b3111fca0a130680
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