Systematic functional analysis of kinases in the fungal pathogen Cryptococcus neoformans

QR Code

Systematic functional analysis of kinases in the fungal pathogen Cryptococcus neoformans

Cryptococcus neoformans is the leading cause of death by fungal meningoencephalitis. Here, the authors study the roles played by 129 putative kinases in the growth and virulence of C. neoformans, identifying potential targets for development of anticryptococcal drugs.

Enregistré dans:

Détails bibliographiques
Auteurs principaux:	Kyung-Tae Lee, Yee-Seul So, Dong-Hoon Yang, Kwang-Woo Jung, Jaeyoung Choi, Dong-Gi Lee, Hyojeong Kwon, Juyeong Jang, Li Li Wang, Soohyun Cha, Gena Lee Meyers, Eunji Jeong, Jae-Hyung Jin, Yeonseon Lee, Joohyeon Hong, Soohyun Bang, Je-Hyun Ji, Goun Park, Hyo-Jeong Byun, Sung Woo Park, Young-Min Park, Gloria Adedoyin, Taeyup Kim, Anna F. Averette, Jong-Soon Choi, Joseph Heitman, Eunji Cheong, Yong-Hwan Lee, Yong-Sun Bahn
Format:	article
Langue:	EN
Publié:	Nature Portfolio 2016
Sujets:	Science Q
Accès en ligne:	https://doaj.org/article/3a1ac90e57ee4c81b3111fca0a130680
Tags:	Ajouter un tag Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires

Genome-wide functional analysis of phosphatases in the pathogenic fungus Cryptococcus neoformans
par: Jae-Hyung Jin, et autres
Publié: (2020)

Fungal kinases and transcription factors regulating brain infection in Cryptococcus neoformans
par: Kyung-Tae Lee, et autres
Publié: (2020)

9-O-butyl-13-(4-isopropylbenzyl)berberine, KR-72, is a potent antifungal agent that inhibits the growth of Cryptococcus neoformans by regulating gene expression.
par: Soohyun Bang, et autres
Publié: (2014)

Unraveling Melanin Biosynthesis and Signaling Networks in <named-content content-type="genus-species">Cryptococcus neoformans</named-content>
par: Dongpil Lee, et autres
Publié: (2019)

Adenylyl Cyclase and Protein Kinase A Play Redundant and Distinct Roles in Growth, Differentiation, Antifungal Drug Resistance, and Pathogenicity of <i>Candida auris</i>
par: Ji-Seok Kim, et autres
Publié: (2021)

Rad53- and Chk1-Dependent DNA Damage Response Pathways Cooperatively Promote Fungal Pathogenesis and Modulate Antifungal Drug Susceptibility
par: Kwang-Woo Jung, et autres
Publié: (2019)

A novel method for extraction, quantification, and identification of microplastics in CreamType of cosmetic products
par: Soohyun Lee, et autres
Publié: (2021)

An Evaluation of the in vivo Safety of Nonporous Silica Nanoparticles: Ocular Topical Administration versus Oral Administration
par: Martha Kim, et autres
Publié: (2017)

Colorimetric detection of individual biothiols by tailor made reactions with silver nanoprisms
par: Pei Li, et autres
Publié: (2021)

Pepper CaREL1, a ubiquitin E3 ligase, regulates drought tolerance via the ABA-signalling pathway
par: Chae Woo Lim, et autres
Publié: (2017)

Organic Dye-Derived N, S Co-Doped Porous Carbon Hosts for Effective Lithium Polysulfide Confinement in Lithium–Sulfur Batteries
par: Eunji Kim, et autres
Publié: (2021)

MemBox: Shared Memory Device for Memory-Centric Computing Applicable to Deep Learning Problems
par: Yongseok Choi, et autres
Publié: (2021)

Machine learning-based automated classification of headache disorders using patient-reported questionnaires
par: Junmo Kwon, et autres
Publié: (2020)

Structural analysis of fungal pathogenicity-related casein kinase α subunit, Cka1, in the human fungal pathogen Cryptococcus neoformans
par: Belinda X. Ong, et autres
Publié: (2019)

A Translation-Aborting Small Open Reading Frame in the Intergenic Region Promotes Translation of a Mg <sup>2+</sup> Transporter in <i>Salmonella</i> Typhimurium
par: Eunna Choi, et autres
Publié: (2021)

Decreased Incidence of Pediatric Intussusception during COVID-19
par: Jun Sung Park, et autres
Publié: (2021)

Enhanced detection of single-cell-secreted proteins using a fluorescent immunoassay on the protein-G-terminated glass substrate
par: Jeong Y, et autres
Publié: (2015)

Enhanced detection of single-cell-secreted proteins using a fluorescent immunoassay on the protein-G-terminated glass substrate [Corrigendum]
par: Jeong Y, et autres
Publié: (2016)

Neural Network Physically Unclonable Function: A Trainable Physically Unclonable Function System with Unassailability against Deep Learning Attacks Using Memristor Array
par: Junkyu Park, et autres
Publié: (2021)

Unraveling Fungal Radiation Resistance Regulatory Networks through the Genome-Wide Transcriptome and Genetic Analyses of <named-content content-type="genus-species">Cryptococcus neoformans</named-content>
par: Kwang-Woo Jung, et autres
Publié: (2016)

Earthquakes and very deep groundwater perturbation mutually induced
par: Dugin Kaown, et autres
Publié: (2021)

Risk of ischaemic stroke in patients with transient global amnesia: a propensity-matched cohort study
par: Jin-Man Jung, et autres

Photopatterned microswimmers with programmable motion without external stimuli
par: Yeongjae Choi, et autres
Publié: (2021)

Ocular surface disorders associated with the use of dupilumab based on WHO VigiBase
par: Sunny Park, et autres
Publié: (2021)

Effectiveness of the Korean National Cancer Screening Program in reducing breast cancer mortality
par: Eunji Choi, et autres
Publié: (2021)

Marine cyanobacterium Spirulina maxima as an alternate to the animal cell culture medium supplement
par: Younsik Jeong, et autres
Publié: (2021)

A C1069G SNP of the MC4R gene and its association with economic traits in Korean native cattle (brown, brindle, and black)
par: Lee,Youngsub, et autres
Publié: (2013)

Comparison of Risk of Pneumonia Caused by Fluticasone Propionate versus Budesonide in Chronic Obstructive Pulmonary Disease: A Nationwide Retrospective Cohort Study
par: Choi JH, et autres
Publié: (2021)

Bee venom-derived antimicrobial peptide melectin has broad-spectrum potency, cell selectivity, and salt-resistant properties
par: Su Jin Ko, et autres
Publié: (2020)

Surface to bulk Fermi arcs via Weyl nodes as topological defects
par: Kun Woo Kim, et autres
Publié: (2016)

Transparent and attachable ionic communicators based on self-cleanable triboelectric nanogenerators
par: Younghoon Lee, et autres
Publié: (2018)

Lipid raft‐disrupting miltefosine preferentially induces the death of colorectal cancer stem‐like cells
par: So‐Yeon Park, et autres
Publié: (2021)

CT texture analysis of tonsil cancer: Discrimination from normal palatine tonsils.
par: Tae-Yoon Kim, et autres
Publié: (2021)

Shape and Composition Control of Monodisperse Hybrid Pt-CoO Nanocrystals by Controlling the Reaction Kinetics with Additives
par: Hyunje Woo, et autres
Publié: (2017)

Age-dependent shifts and spatial variation in the diet of endangered Black-faced Spoonbill (Platalea minor) chicks.
par: Min-Su Jeong, et autres
Publié: (2021)

Risk of fracture according to glucocorticoid use after renal biopsy: a nationwide population-based study
par: Eunyoung Lee, et autres
Publié: (2020)

Epidemiological characteristics of cancers in patients with end-stage kidney disease: a Korean nationwide study
par: Min-Jeong Lee, et autres
Publié: (2021)

Core <italic toggle="yes">N</italic>-Glycan Structures Are Critical for the Pathogenicity of <named-content content-type="genus-species">Cryptococcus neoformans</named-content> by Modulating Host Cell Death
par: Eun Jung Thak, et autres
Publié: (2020)

Superior pedal function recovery of newly designed three spike insole over total contact insole in refractory plantar fasciitis: A randomized, double-blinded, non-inferiority study.
par: Dong Woo Shim, et autres
Publié: (2021)

Covalent, Non-Covalent, Encapsulated Nanodrug Regulate the Fate of Intra- and Extracellular Trafficking: Impact on Cancer and Normal Cells
par: Sang-Woo Kim, et autres
Publié: (2017)