Plexins function in epithelial repair in both Drosophila and zebrafish

Plexins are semaphorin receptors and are well known for their roles in neuronal pathfinding. Here the authors describe a role for Plexin A in healing damaged epithelia in Drosophila and zebrafish. In Drosophila, Plexin A inhibits the GTPase Rap1 to allow epithelial remodelling to facilitate wound re...

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Autores principales:	Sa Kan Yoo, Heath G. Pascoe, Telmo Pereira, Shu Kondo, Antonio Jacinto, Xuewu Zhang, Iswar K. Hariharan
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/3a1bb84c3e344ad8980c9438804e4793
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spelling	oai:doaj.org-article:3a1bb84c3e344ad8980c9438804e47932021-12-02T17:32:21ZPlexins function in epithelial repair in both Drosophila and zebrafish10.1038/ncomms122822041-1723https://doaj.org/article/3a1bb84c3e344ad8980c9438804e47932016-07-01T00:00:00Zhttps://doi.org/10.1038/ncomms12282https://doaj.org/toc/2041-1723Plexins are semaphorin receptors and are well known for their roles in neuronal pathfinding. Here the authors describe a role for Plexin A in healing damaged epithelia in Drosophila and zebrafish. In Drosophila, Plexin A inhibits the GTPase Rap1 to allow epithelial remodelling to facilitate wound repair.Sa Kan YooHeath G. PascoeTelmo PereiraShu KondoAntonio JacintoXuewu ZhangIswar K. HariharanNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Sa Kan Yoo Heath G. Pascoe Telmo Pereira Shu Kondo Antonio Jacinto Xuewu Zhang Iswar K. Hariharan Plexins function in epithelial repair in both Drosophila and zebrafish
description	Plexins are semaphorin receptors and are well known for their roles in neuronal pathfinding. Here the authors describe a role for Plexin A in healing damaged epithelia in Drosophila and zebrafish. In Drosophila, Plexin A inhibits the GTPase Rap1 to allow epithelial remodelling to facilitate wound repair.
format	article
author	Sa Kan Yoo Heath G. Pascoe Telmo Pereira Shu Kondo Antonio Jacinto Xuewu Zhang Iswar K. Hariharan
author_facet	Sa Kan Yoo Heath G. Pascoe Telmo Pereira Shu Kondo Antonio Jacinto Xuewu Zhang Iswar K. Hariharan
author_sort	Sa Kan Yoo
title	Plexins function in epithelial repair in both Drosophila and zebrafish
title_short	Plexins function in epithelial repair in both Drosophila and zebrafish
title_full	Plexins function in epithelial repair in both Drosophila and zebrafish
title_fullStr	Plexins function in epithelial repair in both Drosophila and zebrafish
title_full_unstemmed	Plexins function in epithelial repair in both Drosophila and zebrafish
title_sort	plexins function in epithelial repair in both drosophila and zebrafish
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/3a1bb84c3e344ad8980c9438804e4793
work_keys_str_mv	AT sakanyoo plexinsfunctioninepithelialrepairinbothdrosophilaandzebrafish AT heathgpascoe plexinsfunctioninepithelialrepairinbothdrosophilaandzebrafish AT telmopereira plexinsfunctioninepithelialrepairinbothdrosophilaandzebrafish AT shukondo plexinsfunctioninepithelialrepairinbothdrosophilaandzebrafish AT antoniojacinto plexinsfunctioninepithelialrepairinbothdrosophilaandzebrafish AT xuewuzhang plexinsfunctioninepithelialrepairinbothdrosophilaandzebrafish AT iswarkhariharan plexinsfunctioninepithelialrepairinbothdrosophilaandzebrafish
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Plexins function in epithelial repair in both Drosophila and zebrafish

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