Structures of tmRNA and SmpB as they transit through the ribosome

Trans-translation, mediated by small protein B (SmpB) and transfer-messenger RNA (tmRNA), enables recycling of the ribosomes stalled on defective mRNAs in bacteria. Here, the authors report structures of the ribosome during trans-translation that reveal a translocation intermediate and elucidate the...

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Autores principales:	Charlotte Guyomar, Gaetano D’Urso, Sophie Chat, Emmanuel Giudice, Reynald Gillet
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/3a1e36fd68b64f30af486fdffef9efd0
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spelling	oai:doaj.org-article:3a1e36fd68b64f30af486fdffef9efd02021-12-02T18:50:57ZStructures of tmRNA and SmpB as they transit through the ribosome10.1038/s41467-021-24881-42041-1723https://doaj.org/article/3a1e36fd68b64f30af486fdffef9efd02021-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-24881-4https://doaj.org/toc/2041-1723Trans-translation, mediated by small protein B (SmpB) and transfer-messenger RNA (tmRNA), enables recycling of the ribosomes stalled on defective mRNAs in bacteria. Here, the authors report structures of the ribosome during trans-translation that reveal a translocation intermediate and elucidate the movements of the tmRNA-SmpB complex in the ribosome.Charlotte GuyomarGaetano D’UrsoSophie ChatEmmanuel GiudiceReynald GilletNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Charlotte Guyomar Gaetano D’Urso Sophie Chat Emmanuel Giudice Reynald Gillet Structures of tmRNA and SmpB as they transit through the ribosome
description	Trans-translation, mediated by small protein B (SmpB) and transfer-messenger RNA (tmRNA), enables recycling of the ribosomes stalled on defective mRNAs in bacteria. Here, the authors report structures of the ribosome during trans-translation that reveal a translocation intermediate and elucidate the movements of the tmRNA-SmpB complex in the ribosome.
format	article
author	Charlotte Guyomar Gaetano D’Urso Sophie Chat Emmanuel Giudice Reynald Gillet
author_facet	Charlotte Guyomar Gaetano D’Urso Sophie Chat Emmanuel Giudice Reynald Gillet
author_sort	Charlotte Guyomar
title	Structures of tmRNA and SmpB as they transit through the ribosome
title_short	Structures of tmRNA and SmpB as they transit through the ribosome
title_full	Structures of tmRNA and SmpB as they transit through the ribosome
title_fullStr	Structures of tmRNA and SmpB as they transit through the ribosome
title_full_unstemmed	Structures of tmRNA and SmpB as they transit through the ribosome
title_sort	structures of tmrna and smpb as they transit through the ribosome
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/3a1e36fd68b64f30af486fdffef9efd0
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Structures of tmRNA and SmpB as they transit through the ribosome

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