A second tubulin binding site on the kinesin-13 motor head domain is important during mitosis.

Kinesin-13s are microtubule (MT) depolymerases different from most other kinesins that move along MTs. Like other kinesins, they have a motor or head domain (HD) containing a tubulin and an ATP binding site. Interestingly, kinesin-13s have an additional binding site (Kin-Tub-2) on the opposite side...

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Auteurs principaux: Dong Zhang, Ana B Asenjo, Michaela Greenbaum, Luping Xie, David J Sharp, Hernando Sosa
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2013
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Accès en ligne:https://doaj.org/article/3a2e77f84f824dfabd3fd7f6445f5e4b
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