A second tubulin binding site on the kinesin-13 motor head domain is important during mitosis.
Kinesin-13s are microtubule (MT) depolymerases different from most other kinesins that move along MTs. Like other kinesins, they have a motor or head domain (HD) containing a tubulin and an ATP binding site. Interestingly, kinesin-13s have an additional binding site (Kin-Tub-2) on the opposite side...
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Autores principales: | Dong Zhang, Ana B Asenjo, Michaela Greenbaum, Luping Xie, David J Sharp, Hernando Sosa |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2013
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Materias: | |
Acceso en línea: | https://doaj.org/article/3a2e77f84f824dfabd3fd7f6445f5e4b |
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