BLOOD MONOCYTE SUBPOPULATIONS DURING UNCOMPLICATED CORONARY ARTERY BYPASS SURGERY

Abstract. We have observed thirty-six patients with coronary artery disease (CAD) who have undergone coronary artery bypass graft (CABG) surgery. In patients with uncomplicated clinical course post-CABG, total lymphocyte counts, T-, B- and NK-cell contents did not significantly differ from baseline...

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Autores principales:	A. S. Golovkin, V. G. Matveeva, I. V. Kudryavtsev, E. V. Grigoriev, E. A. Velikanova, Yu. V. Bairakova
Formato:	article
Lenguaje:	RU
Publicado:	SPb RAACI 2014
Materias:	monocytes cd14 hla-dr coronary artery bypass Immunologic diseases. Allergy RC581-607
Acceso en línea:	https://doaj.org/article/3a30144926a74c64a59f933c868cce3b
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spelling	oai:doaj.org-article:3a30144926a74c64a59f933c868cce3b2021-11-18T08:03:41ZBLOOD MONOCYTE SUBPOPULATIONS DURING UNCOMPLICATED CORONARY ARTERY BYPASS SURGERY1563-06252313-741X10.15789/1563-0625-2012-4-5-305-312https://doaj.org/article/3a30144926a74c64a59f933c868cce3b2014-07-01T00:00:00Zhttps://www.mimmun.ru/mimmun/article/view/421https://doaj.org/toc/1563-0625https://doaj.org/toc/2313-741XAbstract. We have observed thirty-six patients with coronary artery disease (CAD) who have undergone coronary artery bypass graft (CABG) surgery. In patients with uncomplicated clinical course post-CABG, total lymphocyte counts, T-, B- and NK-cell contents did not significantly differ from baseline levels. Meanwhile, the numbers of CD14HIGH and CD14LOW monocyte subpopulations showed significant differences from initial levels at day 1 and day 7 after surgery. The changes in monocyte subsets in blood of patients with and absence of post-surgical septic complications reflected severity of inflammatory response, and development of systemic inflammatory syndrome. In such a case, further studies of peripheral blood monocytes can be both a useful tool for studying the mechanisms of systemic inflammation, as well as a good diagnostic system, in order to assess the patient’s condition and to predict post-surgical clinical outcomes.A. S. GolovkinV. G. MatveevaI. V. KudryavtsevE. V. GrigorievE. A. VelikanovaYu. V. BairakovaSPb RAACIarticlemonocytescd14hla-drcoronary artery bypassImmunologic diseases. AllergyRC581-607RUMedicinskaâ Immunologiâ, Vol 14, Iss 4-5, Pp 305-312 (2014)
institution	DOAJ
collection	DOAJ
language	RU
topic	monocytes cd14 hla-dr coronary artery bypass Immunologic diseases. Allergy RC581-607
spellingShingle	monocytes cd14 hla-dr coronary artery bypass Immunologic diseases. Allergy RC581-607 A. S. Golovkin V. G. Matveeva I. V. Kudryavtsev E. V. Grigoriev E. A. Velikanova Yu. V. Bairakova BLOOD MONOCYTE SUBPOPULATIONS DURING UNCOMPLICATED CORONARY ARTERY BYPASS SURGERY
description	Abstract. We have observed thirty-six patients with coronary artery disease (CAD) who have undergone coronary artery bypass graft (CABG) surgery. In patients with uncomplicated clinical course post-CABG, total lymphocyte counts, T-, B- and NK-cell contents did not significantly differ from baseline levels. Meanwhile, the numbers of CD14HIGH and CD14LOW monocyte subpopulations showed significant differences from initial levels at day 1 and day 7 after surgery. The changes in monocyte subsets in blood of patients with and absence of post-surgical septic complications reflected severity of inflammatory response, and development of systemic inflammatory syndrome. In such a case, further studies of peripheral blood monocytes can be both a useful tool for studying the mechanisms of systemic inflammation, as well as a good diagnostic system, in order to assess the patient’s condition and to predict post-surgical clinical outcomes.
format	article
author	A. S. Golovkin V. G. Matveeva I. V. Kudryavtsev E. V. Grigoriev E. A. Velikanova Yu. V. Bairakova
author_facet	A. S. Golovkin V. G. Matveeva I. V. Kudryavtsev E. V. Grigoriev E. A. Velikanova Yu. V. Bairakova
author_sort	A. S. Golovkin
title	BLOOD MONOCYTE SUBPOPULATIONS DURING UNCOMPLICATED CORONARY ARTERY BYPASS SURGERY
title_short	BLOOD MONOCYTE SUBPOPULATIONS DURING UNCOMPLICATED CORONARY ARTERY BYPASS SURGERY
title_full	BLOOD MONOCYTE SUBPOPULATIONS DURING UNCOMPLICATED CORONARY ARTERY BYPASS SURGERY
title_fullStr	BLOOD MONOCYTE SUBPOPULATIONS DURING UNCOMPLICATED CORONARY ARTERY BYPASS SURGERY
title_full_unstemmed	BLOOD MONOCYTE SUBPOPULATIONS DURING UNCOMPLICATED CORONARY ARTERY BYPASS SURGERY
title_sort	blood monocyte subpopulations during uncomplicated coronary artery bypass surgery
publisher	SPb RAACI
publishDate	2014
url	https://doaj.org/article/3a30144926a74c64a59f933c868cce3b
work_keys_str_mv	AT asgolovkin bloodmonocytesubpopulationsduringuncomplicatedcoronaryarterybypasssurgery AT vgmatveeva bloodmonocytesubpopulationsduringuncomplicatedcoronaryarterybypasssurgery AT ivkudryavtsev bloodmonocytesubpopulationsduringuncomplicatedcoronaryarterybypasssurgery AT evgrigoriev bloodmonocytesubpopulationsduringuncomplicatedcoronaryarterybypasssurgery AT eavelikanova bloodmonocytesubpopulationsduringuncomplicatedcoronaryarterybypasssurgery AT yuvbairakova bloodmonocytesubpopulationsduringuncomplicatedcoronaryarterybypasssurgery
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BLOOD MONOCYTE SUBPOPULATIONS DURING UNCOMPLICATED CORONARY ARTERY BYPASS SURGERY

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