Polymeric Micro/Nanocarriers and Motors for Cargo Transport and Phototriggered Delivery

Smart polymer-based micro/nanoassemblies have emerged as a promising alternative for transporting and delivering a myriad of cargo. Cargo encapsulation into (or linked to) polymeric micro/nanocarrier (PC) strategies may help to conserve cargo activity and functionality when interacting with its surr...

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Autores principales:	Pedro Mena-Giraldo, Jahir Orozco
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	photosensitive micro/nanocarriers polymeric nanomicelles polymeric nanocarriers nanopolymersomes cargo photodelivery targeting cells Organic chemistry QD241-441
Acceso en línea:	https://doaj.org/article/3a37f6868ff14f95b152494c5e17b3d4
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spelling	oai:doaj.org-article:3a37f6868ff14f95b152494c5e17b3d42021-11-25T18:48:20ZPolymeric Micro/Nanocarriers and Motors for Cargo Transport and Phototriggered Delivery10.3390/polym132239202073-4360https://doaj.org/article/3a37f6868ff14f95b152494c5e17b3d42021-11-01T00:00:00Zhttps://www.mdpi.com/2073-4360/13/22/3920https://doaj.org/toc/2073-4360Smart polymer-based micro/nanoassemblies have emerged as a promising alternative for transporting and delivering a myriad of cargo. Cargo encapsulation into (or linked to) polymeric micro/nanocarrier (PC) strategies may help to conserve cargo activity and functionality when interacting with its surroundings in its journey to the target. PCs for cargo phototriggering allow for excellent spatiotemporal control via irradiation as an external stimulus, thus regulating the delivery kinetics of cargo and potentially increasing its therapeutic effect. Micromotors based on PCs offer an accelerated cargo–medium interaction for biomedical, environmental, and many other applications. This review collects the recent achievements in PC development based on nanomicelles, nanospheres, and nanopolymersomes, among others, with enhanced properties to increase cargo protection and cargo release efficiency triggered by ultraviolet (UV) and near-infrared (NIR) irradiation, including light-stimulated polymeric micromotors for propulsion, cargo transport, biosensing, and photo-thermal therapy. We emphasize the challenges of positioning PCs as drug delivery systems, as well as the outstanding opportunities of light-stimulated polymeric micromotors for practical applications.Pedro Mena-GiraldoJahir OrozcoMDPI AGarticlephotosensitive micro/nanocarrierspolymeric nanomicellespolymeric nanocarriersnanopolymersomescargo photodeliverytargeting cellsOrganic chemistryQD241-441ENPolymers, Vol 13, Iss 3920, p 3920 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	photosensitive micro/nanocarriers polymeric nanomicelles polymeric nanocarriers nanopolymersomes cargo photodelivery targeting cells Organic chemistry QD241-441
spellingShingle	photosensitive micro/nanocarriers polymeric nanomicelles polymeric nanocarriers nanopolymersomes cargo photodelivery targeting cells Organic chemistry QD241-441 Pedro Mena-Giraldo Jahir Orozco Polymeric Micro/Nanocarriers and Motors for Cargo Transport and Phototriggered Delivery
description	Smart polymer-based micro/nanoassemblies have emerged as a promising alternative for transporting and delivering a myriad of cargo. Cargo encapsulation into (or linked to) polymeric micro/nanocarrier (PC) strategies may help to conserve cargo activity and functionality when interacting with its surroundings in its journey to the target. PCs for cargo phototriggering allow for excellent spatiotemporal control via irradiation as an external stimulus, thus regulating the delivery kinetics of cargo and potentially increasing its therapeutic effect. Micromotors based on PCs offer an accelerated cargo–medium interaction for biomedical, environmental, and many other applications. This review collects the recent achievements in PC development based on nanomicelles, nanospheres, and nanopolymersomes, among others, with enhanced properties to increase cargo protection and cargo release efficiency triggered by ultraviolet (UV) and near-infrared (NIR) irradiation, including light-stimulated polymeric micromotors for propulsion, cargo transport, biosensing, and photo-thermal therapy. We emphasize the challenges of positioning PCs as drug delivery systems, as well as the outstanding opportunities of light-stimulated polymeric micromotors for practical applications.
format	article
author	Pedro Mena-Giraldo Jahir Orozco
author_facet	Pedro Mena-Giraldo Jahir Orozco
author_sort	Pedro Mena-Giraldo
title	Polymeric Micro/Nanocarriers and Motors for Cargo Transport and Phototriggered Delivery
title_short	Polymeric Micro/Nanocarriers and Motors for Cargo Transport and Phototriggered Delivery
title_full	Polymeric Micro/Nanocarriers and Motors for Cargo Transport and Phototriggered Delivery
title_fullStr	Polymeric Micro/Nanocarriers and Motors for Cargo Transport and Phototriggered Delivery
title_full_unstemmed	Polymeric Micro/Nanocarriers and Motors for Cargo Transport and Phototriggered Delivery
title_sort	polymeric micro/nanocarriers and motors for cargo transport and phototriggered delivery
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/3a37f6868ff14f95b152494c5e17b3d4
work_keys_str_mv	AT pedromenagiraldo polymericmicronanocarriersandmotorsforcargotransportandphototriggereddelivery AT jahirorozco polymericmicronanocarriersandmotorsforcargotransportandphototriggereddelivery
_version_	1718410705298784256

Polymeric Micro/Nanocarriers and Motors for Cargo Transport and Phototriggered Delivery

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