ARMMs as a versatile platform for intracellular delivery of macromolecules

One of the challenges of biologic drug therapy is delivery into target cells and tissues. Here the authors present ARMMs (arrestin domain containing protein 1 mediated microvesicles) as a versatile platform for packaging and delivery of a myriad of molecules, including p53, RNAs and CRISPR-Cas9.

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Autores principales: Qiyu Wang, Jiujiu Yu, Tatenda Kadungure, Joseph Beyene, Hong Zhang, Quan Lu
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/3a4b3a6a3eda46ca879fb9d6819234f2
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spelling oai:doaj.org-article:3a4b3a6a3eda46ca879fb9d6819234f22021-12-02T15:34:19ZARMMs as a versatile platform for intracellular delivery of macromolecules10.1038/s41467-018-03390-x2041-1723https://doaj.org/article/3a4b3a6a3eda46ca879fb9d6819234f22018-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-03390-xhttps://doaj.org/toc/2041-1723One of the challenges of biologic drug therapy is delivery into target cells and tissues. Here the authors present ARMMs (arrestin domain containing protein 1 mediated microvesicles) as a versatile platform for packaging and delivery of a myriad of molecules, including p53, RNAs and CRISPR-Cas9.Qiyu WangJiujiu YuTatenda KadungureJoseph BeyeneHong ZhangQuan LuNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-7 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Qiyu Wang
Jiujiu Yu
Tatenda Kadungure
Joseph Beyene
Hong Zhang
Quan Lu
ARMMs as a versatile platform for intracellular delivery of macromolecules
description One of the challenges of biologic drug therapy is delivery into target cells and tissues. Here the authors present ARMMs (arrestin domain containing protein 1 mediated microvesicles) as a versatile platform for packaging and delivery of a myriad of molecules, including p53, RNAs and CRISPR-Cas9.
format article
author Qiyu Wang
Jiujiu Yu
Tatenda Kadungure
Joseph Beyene
Hong Zhang
Quan Lu
author_facet Qiyu Wang
Jiujiu Yu
Tatenda Kadungure
Joseph Beyene
Hong Zhang
Quan Lu
author_sort Qiyu Wang
title ARMMs as a versatile platform for intracellular delivery of macromolecules
title_short ARMMs as a versatile platform for intracellular delivery of macromolecules
title_full ARMMs as a versatile platform for intracellular delivery of macromolecules
title_fullStr ARMMs as a versatile platform for intracellular delivery of macromolecules
title_full_unstemmed ARMMs as a versatile platform for intracellular delivery of macromolecules
title_sort armms as a versatile platform for intracellular delivery of macromolecules
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/3a4b3a6a3eda46ca879fb9d6819234f2
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AT tatendakadungure armmsasaversatileplatformforintracellulardeliveryofmacromolecules
AT josephbeyene armmsasaversatileplatformforintracellulardeliveryofmacromolecules
AT hongzhang armmsasaversatileplatformforintracellulardeliveryofmacromolecules
AT quanlu armmsasaversatileplatformforintracellulardeliveryofmacromolecules
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