Effects of 1 MHz Therapeutic Ultrasound on Limb Blood Flow and Microvascular Reactivity: A Randomized Pilot Trial

A randomized, double-blind, placebo-controlled, cross-over study where continuous therapeutic ultrasound (CUS; at 0.4 W/cm<sup>2</sup>), pulsed therapeutic ultrasound (PUS; at 20% duty cycle, 0.08 W/cm<sup>2</sup>), both at 1 MHz, and placebo (equipment on, no energy provided...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Megan Waters, Branko Miljkovic, Jozelyn Rascon, Manuel Gomez, Alvaro N. Gurovich
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	therapeutic ultrasound blood flow microvascular function Medicine R
Acceso en línea:	https://doaj.org/article/3a4cdf767a7d44229e521da47a816741
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:3a4cdf767a7d44229e521da47a816741
record_format	dspace
spelling	oai:doaj.org-article:3a4cdf767a7d44229e521da47a8167412021-11-11T16:33:54ZEffects of 1 MHz Therapeutic Ultrasound on Limb Blood Flow and Microvascular Reactivity: A Randomized Pilot Trial10.3390/ijerph1821114441660-46011661-7827https://doaj.org/article/3a4cdf767a7d44229e521da47a8167412021-10-01T00:00:00Zhttps://www.mdpi.com/1660-4601/18/21/11444https://doaj.org/toc/1661-7827https://doaj.org/toc/1660-4601A randomized, double-blind, placebo-controlled, cross-over study where continuous therapeutic ultrasound (CUS; at 0.4 W/cm<sup>2</sup>), pulsed therapeutic ultrasound (PUS; at 20% duty cycle, 0.08 W/cm<sup>2</sup>), both at 1 MHz, and placebo (equipment on, no energy provided) were randomized and applied over the forearm of the non-dominant arm for 5 min in 10 young, healthy individuals. Absolute and peak forearm blood flow (FBF) were measured via Venous Occlusion Plethysmography. FBF was measured before, halfway, and after (immediately and 5 min after) the therapeutic ultrasound (TUS) intervention. Post-ischemic peak FBF was measured 10 min before and 10 min after the TUS intervention. A two-way repeated measures ANOVA (group × time) was selected to assess differences in FBF before, during, and after TUS treatment, and for peak FBF before and after TUS treatment. FBF increased 5 min after TUS in CUS compared to placebo (2.96 ± 1.04 vs. 2.09 ± 0.63 mL/min/100 mL of tissue, <i>p</i> < 0.05). PUS resulted in the greatest increase in Peak FBF at 10 min after US (Δ = 3.96 ± 2.02 mL/min/100 mL of tissue, <i>p</i> = 0.06). CUS at 1 MHz was an effective treatment modality for increasing FBF up to 5 min after intervention, but PUS resulted in the greatest increase in peak FBF at 10 min after intervention.Megan WatersBranko MiljkovicJozelyn RasconManuel GomezAlvaro N. GurovichMDPI AGarticletherapeutic ultrasoundblood flowmicrovascular functionMedicineRENInternational Journal of Environmental Research and Public Health, Vol 18, Iss 11444, p 11444 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	therapeutic ultrasound blood flow microvascular function Medicine R
spellingShingle	therapeutic ultrasound blood flow microvascular function Medicine R Megan Waters Branko Miljkovic Jozelyn Rascon Manuel Gomez Alvaro N. Gurovich Effects of 1 MHz Therapeutic Ultrasound on Limb Blood Flow and Microvascular Reactivity: A Randomized Pilot Trial
description	A randomized, double-blind, placebo-controlled, cross-over study where continuous therapeutic ultrasound (CUS; at 0.4 W/cm<sup>2</sup>), pulsed therapeutic ultrasound (PUS; at 20% duty cycle, 0.08 W/cm<sup>2</sup>), both at 1 MHz, and placebo (equipment on, no energy provided) were randomized and applied over the forearm of the non-dominant arm for 5 min in 10 young, healthy individuals. Absolute and peak forearm blood flow (FBF) were measured via Venous Occlusion Plethysmography. FBF was measured before, halfway, and after (immediately and 5 min after) the therapeutic ultrasound (TUS) intervention. Post-ischemic peak FBF was measured 10 min before and 10 min after the TUS intervention. A two-way repeated measures ANOVA (group × time) was selected to assess differences in FBF before, during, and after TUS treatment, and for peak FBF before and after TUS treatment. FBF increased 5 min after TUS in CUS compared to placebo (2.96 ± 1.04 vs. 2.09 ± 0.63 mL/min/100 mL of tissue, <i>p</i> < 0.05). PUS resulted in the greatest increase in Peak FBF at 10 min after US (Δ = 3.96 ± 2.02 mL/min/100 mL of tissue, <i>p</i> = 0.06). CUS at 1 MHz was an effective treatment modality for increasing FBF up to 5 min after intervention, but PUS resulted in the greatest increase in peak FBF at 10 min after intervention.
format	article
author	Megan Waters Branko Miljkovic Jozelyn Rascon Manuel Gomez Alvaro N. Gurovich
author_facet	Megan Waters Branko Miljkovic Jozelyn Rascon Manuel Gomez Alvaro N. Gurovich
author_sort	Megan Waters
title	Effects of 1 MHz Therapeutic Ultrasound on Limb Blood Flow and Microvascular Reactivity: A Randomized Pilot Trial
title_short	Effects of 1 MHz Therapeutic Ultrasound on Limb Blood Flow and Microvascular Reactivity: A Randomized Pilot Trial
title_full	Effects of 1 MHz Therapeutic Ultrasound on Limb Blood Flow and Microvascular Reactivity: A Randomized Pilot Trial
title_fullStr	Effects of 1 MHz Therapeutic Ultrasound on Limb Blood Flow and Microvascular Reactivity: A Randomized Pilot Trial
title_full_unstemmed	Effects of 1 MHz Therapeutic Ultrasound on Limb Blood Flow and Microvascular Reactivity: A Randomized Pilot Trial
title_sort	effects of 1 mhz therapeutic ultrasound on limb blood flow and microvascular reactivity: a randomized pilot trial
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/3a4cdf767a7d44229e521da47a816741
work_keys_str_mv	AT meganwaters effectsof1mhztherapeuticultrasoundonlimbbloodflowandmicrovascularreactivityarandomizedpilottrial AT brankomiljkovic effectsof1mhztherapeuticultrasoundonlimbbloodflowandmicrovascularreactivityarandomizedpilottrial AT jozelynrascon effectsof1mhztherapeuticultrasoundonlimbbloodflowandmicrovascularreactivityarandomizedpilottrial AT manuelgomez effectsof1mhztherapeuticultrasoundonlimbbloodflowandmicrovascularreactivityarandomizedpilottrial AT alvarongurovich effectsof1mhztherapeuticultrasoundonlimbbloodflowandmicrovascularreactivityarandomizedpilottrial
_version_	1718432291059924992

Effects of 1 MHz Therapeutic Ultrasound on Limb Blood Flow and Microvascular Reactivity: A Randomized Pilot Trial

Ejemplares similares