Concerted ESCRT and clathrin recruitment waves define the timing and morphology of intraluminal vesicle formation
Intraluminal vesicles are formed by the endosomal sorting complex required for transport (ESCRT) machinery. Here, the authors unravel the timing of vesicle budding, and that endosomal clathrin regulates concerted recruitment of ESCRT subcomplexes, required for efficient membrane remodeling.
Guardado en:
Autores principales: | , , , , , , , , |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2018
|
Materias: | |
Acceso en línea: | https://doaj.org/article/3a4d89a071f847dfb021b798caff85ef |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
id |
oai:doaj.org-article:3a4d89a071f847dfb021b798caff85ef |
---|---|
record_format |
dspace |
spelling |
oai:doaj.org-article:3a4d89a071f847dfb021b798caff85ef2021-12-02T15:34:20ZConcerted ESCRT and clathrin recruitment waves define the timing and morphology of intraluminal vesicle formation10.1038/s41467-018-05345-82041-1723https://doaj.org/article/3a4d89a071f847dfb021b798caff85ef2018-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-05345-8https://doaj.org/toc/2041-1723Intraluminal vesicles are formed by the endosomal sorting complex required for transport (ESCRT) machinery. Here, the authors unravel the timing of vesicle budding, and that endosomal clathrin regulates concerted recruitment of ESCRT subcomplexes, required for efficient membrane remodeling.Eva Maria WenzelSebastian Wolfgang SchultzKay Oliver SchinkNina Marie PedersenViola NähseAndreas CarlsonAndreas BrechHarald StenmarkCamilla RaiborgNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-18 (2018) |
institution |
DOAJ |
collection |
DOAJ |
language |
EN |
topic |
Science Q |
spellingShingle |
Science Q Eva Maria Wenzel Sebastian Wolfgang Schultz Kay Oliver Schink Nina Marie Pedersen Viola Nähse Andreas Carlson Andreas Brech Harald Stenmark Camilla Raiborg Concerted ESCRT and clathrin recruitment waves define the timing and morphology of intraluminal vesicle formation |
description |
Intraluminal vesicles are formed by the endosomal sorting complex required for transport (ESCRT) machinery. Here, the authors unravel the timing of vesicle budding, and that endosomal clathrin regulates concerted recruitment of ESCRT subcomplexes, required for efficient membrane remodeling. |
format |
article |
author |
Eva Maria Wenzel Sebastian Wolfgang Schultz Kay Oliver Schink Nina Marie Pedersen Viola Nähse Andreas Carlson Andreas Brech Harald Stenmark Camilla Raiborg |
author_facet |
Eva Maria Wenzel Sebastian Wolfgang Schultz Kay Oliver Schink Nina Marie Pedersen Viola Nähse Andreas Carlson Andreas Brech Harald Stenmark Camilla Raiborg |
author_sort |
Eva Maria Wenzel |
title |
Concerted ESCRT and clathrin recruitment waves define the timing and morphology of intraluminal vesicle formation |
title_short |
Concerted ESCRT and clathrin recruitment waves define the timing and morphology of intraluminal vesicle formation |
title_full |
Concerted ESCRT and clathrin recruitment waves define the timing and morphology of intraluminal vesicle formation |
title_fullStr |
Concerted ESCRT and clathrin recruitment waves define the timing and morphology of intraluminal vesicle formation |
title_full_unstemmed |
Concerted ESCRT and clathrin recruitment waves define the timing and morphology of intraluminal vesicle formation |
title_sort |
concerted escrt and clathrin recruitment waves define the timing and morphology of intraluminal vesicle formation |
publisher |
Nature Portfolio |
publishDate |
2018 |
url |
https://doaj.org/article/3a4d89a071f847dfb021b798caff85ef |
work_keys_str_mv |
AT evamariawenzel concertedescrtandclathrinrecruitmentwavesdefinethetimingandmorphologyofintraluminalvesicleformation AT sebastianwolfgangschultz concertedescrtandclathrinrecruitmentwavesdefinethetimingandmorphologyofintraluminalvesicleformation AT kayoliverschink concertedescrtandclathrinrecruitmentwavesdefinethetimingandmorphologyofintraluminalvesicleformation AT ninamariepedersen concertedescrtandclathrinrecruitmentwavesdefinethetimingandmorphologyofintraluminalvesicleformation AT violanahse concertedescrtandclathrinrecruitmentwavesdefinethetimingandmorphologyofintraluminalvesicleformation AT andreascarlson concertedescrtandclathrinrecruitmentwavesdefinethetimingandmorphologyofintraluminalvesicleformation AT andreasbrech concertedescrtandclathrinrecruitmentwavesdefinethetimingandmorphologyofintraluminalvesicleformation AT haraldstenmark concertedescrtandclathrinrecruitmentwavesdefinethetimingandmorphologyofintraluminalvesicleformation AT camillaraiborg concertedescrtandclathrinrecruitmentwavesdefinethetimingandmorphologyofintraluminalvesicleformation |
_version_ |
1718386832183394304 |