Concerted ESCRT and clathrin recruitment waves define the timing and morphology of intraluminal vesicle formation

Intraluminal vesicles are formed by the endosomal sorting complex required for transport (ESCRT) machinery. Here, the authors unravel the timing of vesicle budding, and that endosomal clathrin regulates concerted recruitment of ESCRT subcomplexes, required for efficient membrane remodeling.

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Autores principales: Eva Maria Wenzel, Sebastian Wolfgang Schultz, Kay Oliver Schink, Nina Marie Pedersen, Viola Nähse, Andreas Carlson, Andreas Brech, Harald Stenmark, Camilla Raiborg
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Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/3a4d89a071f847dfb021b798caff85ef
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spelling oai:doaj.org-article:3a4d89a071f847dfb021b798caff85ef2021-12-02T15:34:20ZConcerted ESCRT and clathrin recruitment waves define the timing and morphology of intraluminal vesicle formation10.1038/s41467-018-05345-82041-1723https://doaj.org/article/3a4d89a071f847dfb021b798caff85ef2018-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-05345-8https://doaj.org/toc/2041-1723Intraluminal vesicles are formed by the endosomal sorting complex required for transport (ESCRT) machinery. Here, the authors unravel the timing of vesicle budding, and that endosomal clathrin regulates concerted recruitment of ESCRT subcomplexes, required for efficient membrane remodeling.Eva Maria WenzelSebastian Wolfgang SchultzKay Oliver SchinkNina Marie PedersenViola NähseAndreas CarlsonAndreas BrechHarald StenmarkCamilla RaiborgNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-18 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Eva Maria Wenzel
Sebastian Wolfgang Schultz
Kay Oliver Schink
Nina Marie Pedersen
Viola Nähse
Andreas Carlson
Andreas Brech
Harald Stenmark
Camilla Raiborg
Concerted ESCRT and clathrin recruitment waves define the timing and morphology of intraluminal vesicle formation
description Intraluminal vesicles are formed by the endosomal sorting complex required for transport (ESCRT) machinery. Here, the authors unravel the timing of vesicle budding, and that endosomal clathrin regulates concerted recruitment of ESCRT subcomplexes, required for efficient membrane remodeling.
format article
author Eva Maria Wenzel
Sebastian Wolfgang Schultz
Kay Oliver Schink
Nina Marie Pedersen
Viola Nähse
Andreas Carlson
Andreas Brech
Harald Stenmark
Camilla Raiborg
author_facet Eva Maria Wenzel
Sebastian Wolfgang Schultz
Kay Oliver Schink
Nina Marie Pedersen
Viola Nähse
Andreas Carlson
Andreas Brech
Harald Stenmark
Camilla Raiborg
author_sort Eva Maria Wenzel
title Concerted ESCRT and clathrin recruitment waves define the timing and morphology of intraluminal vesicle formation
title_short Concerted ESCRT and clathrin recruitment waves define the timing and morphology of intraluminal vesicle formation
title_full Concerted ESCRT and clathrin recruitment waves define the timing and morphology of intraluminal vesicle formation
title_fullStr Concerted ESCRT and clathrin recruitment waves define the timing and morphology of intraluminal vesicle formation
title_full_unstemmed Concerted ESCRT and clathrin recruitment waves define the timing and morphology of intraluminal vesicle formation
title_sort concerted escrt and clathrin recruitment waves define the timing and morphology of intraluminal vesicle formation
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/3a4d89a071f847dfb021b798caff85ef
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