IMMUNOLOGICAL FEATURES IN LIVER CIRRHOSIS INDUCED BY HEPATITIS B VIRUS

Abstract. A comparative analysis of immunological data was performed in the patients with HBV-induced liver cirrhosis, and in a group of patients with acute and chronic viral hepatitis B (AVHB, CVHB). Activation of B cell immune compartment (increase in CD22+ lymphocytes and IL4, circulating immune...

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Autores principales:	O. I. Urazova, I. S. Evstigneуeva, K. I. Tchuikova
Formato:	article
Lenguaje:	RU
Publicado:	SPb RAACI 2014
Materias:	hbv-induced liver cirrhosis acute viral hepatitis b chronic viral hepatitis b lymphocytes cytokines Immunologic diseases. Allergy RC581-607
Acceso en línea:	https://doaj.org/article/3a5029c09a1249c9a0038104b7398586
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spelling	oai:doaj.org-article:3a5029c09a1249c9a0038104b73985862021-11-18T08:03:39ZIMMUNOLOGICAL FEATURES IN LIVER CIRRHOSIS INDUCED BY HEPATITIS B VIRUS1563-06252313-741X10.15789/1563-0625-2007-6-597-604https://doaj.org/article/3a5029c09a1249c9a0038104b73985862014-07-01T00:00:00Zhttps://www.mimmun.ru/mimmun/article/view/246https://doaj.org/toc/1563-0625https://doaj.org/toc/2313-741XAbstract. A comparative analysis of immunological data was performed in the patients with HBV-induced liver cirrhosis, and in a group of patients with acute and chronic viral hepatitis B (AVHB, CVHB). Activation of B cell immune compartment (increase in CD22+ lymphocytes and IL4, circulating immune complexes in blood) was demonstrated in patients with liver cirrhosis, being also associated with increased numbers of CD16+ lymphocytes and T-cell deficiency. It was revealed that the differences are most expressed upon comparison of immunologic data from the patients with liver cirrhosis, and AVHB followed by clearance of the virus. When comparing these groups, the differences in immunological state between the patients with liver cirrhosis and CVHB did not depend on the phase of viral replication or integration.O. I. UrazovaI. S. EvstigneуevaK. I. TchuikovaSPb RAACIarticlehbv-induced liver cirrhosisacute viral hepatitis bchronic viral hepatitis blymphocytescytokinesImmunologic diseases. AllergyRC581-607RUMedicinskaâ Immunologiâ, Vol 9, Iss 6, Pp 597-604 (2014)
institution	DOAJ
collection	DOAJ
language	RU
topic	hbv-induced liver cirrhosis acute viral hepatitis b chronic viral hepatitis b lymphocytes cytokines Immunologic diseases. Allergy RC581-607
spellingShingle	hbv-induced liver cirrhosis acute viral hepatitis b chronic viral hepatitis b lymphocytes cytokines Immunologic diseases. Allergy RC581-607 O. I. Urazova I. S. Evstigneуeva K. I. Tchuikova IMMUNOLOGICAL FEATURES IN LIVER CIRRHOSIS INDUCED BY HEPATITIS B VIRUS
description	Abstract. A comparative analysis of immunological data was performed in the patients with HBV-induced liver cirrhosis, and in a group of patients with acute and chronic viral hepatitis B (AVHB, CVHB). Activation of B cell immune compartment (increase in CD22+ lymphocytes and IL4, circulating immune complexes in blood) was demonstrated in patients with liver cirrhosis, being also associated with increased numbers of CD16+ lymphocytes and T-cell deficiency. It was revealed that the differences are most expressed upon comparison of immunologic data from the patients with liver cirrhosis, and AVHB followed by clearance of the virus. When comparing these groups, the differences in immunological state between the patients with liver cirrhosis and CVHB did not depend on the phase of viral replication or integration.
format	article
author	O. I. Urazova I. S. Evstigneуeva K. I. Tchuikova
author_facet	O. I. Urazova I. S. Evstigneуeva K. I. Tchuikova
author_sort	O. I. Urazova
title	IMMUNOLOGICAL FEATURES IN LIVER CIRRHOSIS INDUCED BY HEPATITIS B VIRUS
title_short	IMMUNOLOGICAL FEATURES IN LIVER CIRRHOSIS INDUCED BY HEPATITIS B VIRUS
title_full	IMMUNOLOGICAL FEATURES IN LIVER CIRRHOSIS INDUCED BY HEPATITIS B VIRUS
title_fullStr	IMMUNOLOGICAL FEATURES IN LIVER CIRRHOSIS INDUCED BY HEPATITIS B VIRUS
title_full_unstemmed	IMMUNOLOGICAL FEATURES IN LIVER CIRRHOSIS INDUCED BY HEPATITIS B VIRUS
title_sort	immunological features in liver cirrhosis induced by hepatitis b virus
publisher	SPb RAACI
publishDate	2014
url	https://doaj.org/article/3a5029c09a1249c9a0038104b7398586
work_keys_str_mv	AT oiurazova immunologicalfeaturesinlivercirrhosisinducedbyhepatitisbvirus AT isevstigneueva immunologicalfeaturesinlivercirrhosisinducedbyhepatitisbvirus AT kitchuikova immunologicalfeaturesinlivercirrhosisinducedbyhepatitisbvirus
_version_	1718422537023520768

IMMUNOLOGICAL FEATURES IN LIVER CIRRHOSIS INDUCED BY HEPATITIS B VIRUS

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