Biophysical properties of a tau seed
Abstract Pathogenesis of tauopathies involves conversion of tau monomer into pathological tau conformers that serve as templates to recruit native tau into growing assemblies. Small soluble tau seeds have been proposed to drive pathological tau assembly in vitro, in cells and in vivo. We have previo...
Guardado en:
Autores principales: | Zhiqiang Hou, Dailu Chen, Bryan D. Ryder, Lukasz A. Joachimiak |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/3a52c751ad3f486f923d73a2de32d49c |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Tau local structure shields an amyloid-forming motif and controls aggregation propensity
por: Dailu Chen, et al.
Publicado: (2019) -
DnaJC7 binds natively folded structural elements in tau to inhibit amyloid formation
por: Zhiqiang Hou, et al.
Publicado: (2021) -
Amorphous aggregation of tau in the presence of titanium dioxide nanoparticles: biophysical, computational, and cellular studies
por: Fardanesh A, et al.
Publicado: (2019) -
Development of P301S tau seeded organotypic hippocampal slice cultures to study potential therapeutics
por: James M. McCarthy, et al.
Publicado: (2021) -
Emergence of early alterations in network oscillations and functional connectivity in a tau seeding mouse model of Alzheimer’s disease pathology
por: A. Ahnaou, et al.
Publicado: (2017)