Biophysical properties of a tau seed

Abstract Pathogenesis of tauopathies involves conversion of tau monomer into pathological tau conformers that serve as templates to recruit native tau into growing assemblies. Small soluble tau seeds have been proposed to drive pathological tau assembly in vitro, in cells and in vivo. We have previo...

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Autores principales: Zhiqiang Hou, Dailu Chen, Bryan D. Ryder, Lukasz A. Joachimiak
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/3a52c751ad3f486f923d73a2de32d49c
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