Vms1p is a release factor for the ribosome-associated quality control complex

The ribosome-associated quality control complex (RQC) functions to disassemble stalled ribosomes. Here the authors find that the tRNA hydrolase Vms1 is involved in the release of nascent peptide from stalled ribosomes.

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Bibliographic Details
Main Authors: Olga Zurita Rendón, Eric K. Fredrickson, Conor J. Howard, Jonathan Van Vranken, Sarah Fogarty, Neal D. Tolley, Raghav Kalia, Beatriz A. Osuna, Peter S. Shen, Christopher P. Hill, Adam Frost, Jared Rutter
Format: article
Language:EN
Published: Nature Portfolio 2018
Subjects:
Q
Online Access:https://doaj.org/article/3a55ccb06f334a70b5dd8fbbc32464c7
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Description
Summary:The ribosome-associated quality control complex (RQC) functions to disassemble stalled ribosomes. Here the authors find that the tRNA hydrolase Vms1 is involved in the release of nascent peptide from stalled ribosomes.