Low-dose penicillin in early life induces long-term changes in murine gut microbiota, brain cytokines and behavior

There is concern about potential long-term effects of antibiotics on children’s health. Here Leclercqet al. show, in mice, that low doses of penicillin during late pregnancy and early life induce lasting effects on the offspring, including alterations in gut microbiota, brain cytokine levels and beh...

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Auteurs principaux:	Sophie Leclercq, Firoz M. Mian, Andrew M. Stanisz, Laure B. Bindels, Emmanuel Cambier, Hila Ben-Amram, Omry Koren, Paul Forsythe, John Bienenstock
Format:	article
Langue:	EN
Publié:	Nature Portfolio 2017
Sujets:	Science Q
Accès en ligne:	https://doaj.org/article/3a645dbc48e34e2a8be6439350e75304
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spelling	oai:doaj.org-article:3a645dbc48e34e2a8be6439350e753042021-12-02T14:40:59ZLow-dose penicillin in early life induces long-term changes in murine gut microbiota, brain cytokines and behavior10.1038/ncomms150622041-1723https://doaj.org/article/3a645dbc48e34e2a8be6439350e753042017-04-01T00:00:00Zhttps://doi.org/10.1038/ncomms15062https://doaj.org/toc/2041-1723There is concern about potential long-term effects of antibiotics on children’s health. Here Leclercqet al. show, in mice, that low doses of penicillin during late pregnancy and early life induce lasting effects on the offspring, including alterations in gut microbiota, brain cytokine levels and behaviour.Sophie LeclercqFiroz M. MianAndrew M. StaniszLaure B. BindelsEmmanuel CambierHila Ben-AmramOmry KorenPaul ForsytheJohn BienenstockNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Sophie Leclercq Firoz M. Mian Andrew M. Stanisz Laure B. Bindels Emmanuel Cambier Hila Ben-Amram Omry Koren Paul Forsythe John Bienenstock Low-dose penicillin in early life induces long-term changes in murine gut microbiota, brain cytokines and behavior
description	There is concern about potential long-term effects of antibiotics on children’s health. Here Leclercqet al. show, in mice, that low doses of penicillin during late pregnancy and early life induce lasting effects on the offspring, including alterations in gut microbiota, brain cytokine levels and behaviour.
format	article
author	Sophie Leclercq Firoz M. Mian Andrew M. Stanisz Laure B. Bindels Emmanuel Cambier Hila Ben-Amram Omry Koren Paul Forsythe John Bienenstock
author_facet	Sophie Leclercq Firoz M. Mian Andrew M. Stanisz Laure B. Bindels Emmanuel Cambier Hila Ben-Amram Omry Koren Paul Forsythe John Bienenstock
author_sort	Sophie Leclercq
title	Low-dose penicillin in early life induces long-term changes in murine gut microbiota, brain cytokines and behavior
title_short	Low-dose penicillin in early life induces long-term changes in murine gut microbiota, brain cytokines and behavior
title_full	Low-dose penicillin in early life induces long-term changes in murine gut microbiota, brain cytokines and behavior
title_fullStr	Low-dose penicillin in early life induces long-term changes in murine gut microbiota, brain cytokines and behavior
title_full_unstemmed	Low-dose penicillin in early life induces long-term changes in murine gut microbiota, brain cytokines and behavior
title_sort	low-dose penicillin in early life induces long-term changes in murine gut microbiota, brain cytokines and behavior
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/3a645dbc48e34e2a8be6439350e75304
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Low-dose penicillin in early life induces long-term changes in murine gut microbiota, brain cytokines and behavior

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