Low-dose penicillin in early life induces long-term changes in murine gut microbiota, brain cytokines and behavior
There is concern about potential long-term effects of antibiotics on children’s health. Here Leclercqet al. show, in mice, that low doses of penicillin during late pregnancy and early life induce lasting effects on the offspring, including alterations in gut microbiota, brain cytokine levels and beh...
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Nature Portfolio
2017
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oai:doaj.org-article:3a645dbc48e34e2a8be6439350e753042021-12-02T14:40:59ZLow-dose penicillin in early life induces long-term changes in murine gut microbiota, brain cytokines and behavior10.1038/ncomms150622041-1723https://doaj.org/article/3a645dbc48e34e2a8be6439350e753042017-04-01T00:00:00Zhttps://doi.org/10.1038/ncomms15062https://doaj.org/toc/2041-1723There is concern about potential long-term effects of antibiotics on children’s health. Here Leclercqet al. show, in mice, that low doses of penicillin during late pregnancy and early life induce lasting effects on the offspring, including alterations in gut microbiota, brain cytokine levels and behaviour.Sophie LeclercqFiroz M. MianAndrew M. StaniszLaure B. BindelsEmmanuel CambierHila Ben-AmramOmry KorenPaul ForsytheJohn BienenstockNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-12 (2017) |
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Science Q Sophie Leclercq Firoz M. Mian Andrew M. Stanisz Laure B. Bindels Emmanuel Cambier Hila Ben-Amram Omry Koren Paul Forsythe John Bienenstock Low-dose penicillin in early life induces long-term changes in murine gut microbiota, brain cytokines and behavior |
description |
There is concern about potential long-term effects of antibiotics on children’s health. Here Leclercqet al. show, in mice, that low doses of penicillin during late pregnancy and early life induce lasting effects on the offspring, including alterations in gut microbiota, brain cytokine levels and behaviour. |
format |
article |
author |
Sophie Leclercq Firoz M. Mian Andrew M. Stanisz Laure B. Bindels Emmanuel Cambier Hila Ben-Amram Omry Koren Paul Forsythe John Bienenstock |
author_facet |
Sophie Leclercq Firoz M. Mian Andrew M. Stanisz Laure B. Bindels Emmanuel Cambier Hila Ben-Amram Omry Koren Paul Forsythe John Bienenstock |
author_sort |
Sophie Leclercq |
title |
Low-dose penicillin in early life induces long-term changes in murine gut microbiota, brain cytokines and behavior |
title_short |
Low-dose penicillin in early life induces long-term changes in murine gut microbiota, brain cytokines and behavior |
title_full |
Low-dose penicillin in early life induces long-term changes in murine gut microbiota, brain cytokines and behavior |
title_fullStr |
Low-dose penicillin in early life induces long-term changes in murine gut microbiota, brain cytokines and behavior |
title_full_unstemmed |
Low-dose penicillin in early life induces long-term changes in murine gut microbiota, brain cytokines and behavior |
title_sort |
low-dose penicillin in early life induces long-term changes in murine gut microbiota, brain cytokines and behavior |
publisher |
Nature Portfolio |
publishDate |
2017 |
url |
https://doaj.org/article/3a645dbc48e34e2a8be6439350e75304 |
work_keys_str_mv |
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