Administration of Mung Bean Extract (Phaseolus radiatus) in Increasing Hb and Ferritin Level and Decreasing Malondyaldehide (MDA) Level in Anaemic Rats

BACKGROUND: Mung bean, not only contains protein, carbohydrates, and fats, but also contains iron and vitamin C which are proven to overcome anemia in pregnant woman. High iron levels are potential to increase ROS production through fenton reaction. OBJECTIVE: to prove the administration of mungbea...

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Autores principales:	Heni Wijayanti, Taufiqurrachman Nasihun, Atina Hussaana
Formato:	article
Lenguaje:	EN
Publicado:	Universitas Sultan Agung Semarang 2018
Materias:	Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/3a64d43d12f34555af07ba6d129a1e9a
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spelling	oai:doaj.org-article:3a64d43d12f34555af07ba6d129a1e9a2021-11-25T13:15:53ZAdministration of Mung Bean Extract (Phaseolus radiatus) in Increasing Hb and Ferritin Level and Decreasing Malondyaldehide (MDA) Level in Anaemic Rats2085-15452339-093X10.26532/sainsmed.v8i2.1981https://doaj.org/article/3a64d43d12f34555af07ba6d129a1e9a2018-03-01T00:00:00Zhttp://jurnal.unissula.ac.id/index.php/sainsmedika/article/view/1981https://doaj.org/toc/2085-1545https://doaj.org/toc/2339-093XBACKGROUND: Mung bean, not only contains protein, carbohydrates, and fats, but also contains iron and vitamin C which are proven to overcome anemia in pregnant woman. High iron levels are potential to increase ROS production through fenton reaction. OBJECTIVE: to prove the administration of mungbean can increase Hb and ferritin levels and decreasing malondihaldehyde (MDA) in anaemic rats. METHODS: This research uses Post Test Only Control Group Design. A total of 25 anaemic rats were divided into 5 groups: normal group (Nor-G);negative control group (Neg-G), were given low Fe diet; and treatment group with low Fe and mung bean extract at dose of 0,18g/200g/days (GP-0,18), 0,36g/200g/days (GP-0.36), dan 0,72g/200g/days (GP-0.72). Low Fe diet and mung bean extract were administered for 14 days. Hb levels were measured using Sahli method, ferritine level using Immulite Ferritine Kit, and MDA were measured using TBA. RESULTS: Compare to Nor-G and Neg-G, levels of ferritin and Hb on groups with mung bean extract 0,18g (75.56), 0,36g (90.98) and 0,72g (95.87) were significantly higher (p < 0.05). While MDA levels on groups with mung bean 0,18g (4.646), 0,36g (3.396) and 0,72g (1.92) were significantly lower than on Nor-G and Neg-G groups (p < 0.05). CONCLUSION: The administration of mung bean extract can increase Hb and ferritin, also lower MDA level on anaemic rats.Heni WijayantiTaufiqurrachman NasihunAtina HussaanaUniversitas Sultan Agung SemarangarticleMedicine (General)R5-920ENSains Medika, Vol 8, Iss 2 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine (General) R5-920
spellingShingle	Medicine (General) R5-920 Heni Wijayanti Taufiqurrachman Nasihun Atina Hussaana Administration of Mung Bean Extract (Phaseolus radiatus) in Increasing Hb and Ferritin Level and Decreasing Malondyaldehide (MDA) Level in Anaemic Rats
description	BACKGROUND: Mung bean, not only contains protein, carbohydrates, and fats, but also contains iron and vitamin C which are proven to overcome anemia in pregnant woman. High iron levels are potential to increase ROS production through fenton reaction. OBJECTIVE: to prove the administration of mungbean can increase Hb and ferritin levels and decreasing malondihaldehyde (MDA) in anaemic rats. METHODS: This research uses Post Test Only Control Group Design. A total of 25 anaemic rats were divided into 5 groups: normal group (Nor-G);negative control group (Neg-G), were given low Fe diet; and treatment group with low Fe and mung bean extract at dose of 0,18g/200g/days (GP-0,18), 0,36g/200g/days (GP-0.36), dan 0,72g/200g/days (GP-0.72). Low Fe diet and mung bean extract were administered for 14 days. Hb levels were measured using Sahli method, ferritine level using Immulite Ferritine Kit, and MDA were measured using TBA. RESULTS: Compare to Nor-G and Neg-G, levels of ferritin and Hb on groups with mung bean extract 0,18g (75.56), 0,36g (90.98) and 0,72g (95.87) were significantly higher (p < 0.05). While MDA levels on groups with mung bean 0,18g (4.646), 0,36g (3.396) and 0,72g (1.92) were significantly lower than on Nor-G and Neg-G groups (p < 0.05). CONCLUSION: The administration of mung bean extract can increase Hb and ferritin, also lower MDA level on anaemic rats.
format	article
author	Heni Wijayanti Taufiqurrachman Nasihun Atina Hussaana
author_facet	Heni Wijayanti Taufiqurrachman Nasihun Atina Hussaana
author_sort	Heni Wijayanti
title	Administration of Mung Bean Extract (Phaseolus radiatus) in Increasing Hb and Ferritin Level and Decreasing Malondyaldehide (MDA) Level in Anaemic Rats
title_short	Administration of Mung Bean Extract (Phaseolus radiatus) in Increasing Hb and Ferritin Level and Decreasing Malondyaldehide (MDA) Level in Anaemic Rats
title_full	Administration of Mung Bean Extract (Phaseolus radiatus) in Increasing Hb and Ferritin Level and Decreasing Malondyaldehide (MDA) Level in Anaemic Rats
title_fullStr	Administration of Mung Bean Extract (Phaseolus radiatus) in Increasing Hb and Ferritin Level and Decreasing Malondyaldehide (MDA) Level in Anaemic Rats
title_full_unstemmed	Administration of Mung Bean Extract (Phaseolus radiatus) in Increasing Hb and Ferritin Level and Decreasing Malondyaldehide (MDA) Level in Anaemic Rats
title_sort	administration of mung bean extract (phaseolus radiatus) in increasing hb and ferritin level and decreasing malondyaldehide (mda) level in anaemic rats
publisher	Universitas Sultan Agung Semarang
publishDate	2018
url	https://doaj.org/article/3a64d43d12f34555af07ba6d129a1e9a
work_keys_str_mv	AT heniwijayanti administrationofmungbeanextractphaseolusradiatusinincreasinghbandferritinlevelanddecreasingmalondyaldehidemdalevelinanaemicrats AT taufiqurrachmannasihun administrationofmungbeanextractphaseolusradiatusinincreasinghbandferritinlevelanddecreasingmalondyaldehidemdalevelinanaemicrats AT atinahussaana administrationofmungbeanextractphaseolusradiatusinincreasinghbandferritinlevelanddecreasingmalondyaldehidemdalevelinanaemicrats
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Administration of Mung Bean Extract (Phaseolus radiatus) in Increasing Hb and Ferritin Level and Decreasing Malondyaldehide (MDA) Level in Anaemic Rats

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