A Mutation-Related Long Noncoding RNA Signature of Genome Instability Predicts Immune Infiltration and Hepatocellular Carcinoma Prognosis

A Mutation-Related Long Noncoding RNA Signature of Genome Instability Predicts Immune Infiltration and Hepatocellular Carcinoma Prognosis

Background: Long noncoding RNAs (lncRNAs) have been discovered to play a regulatory role in genomic instability (GI), which participates in the carcinogenesis of various cancers, including hepatocellular carcinoma (HCC). We endeavored to establish a GI-derived lncRNA signature (GILncSig) as a potent...

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Autores principales: Jianhua Wu, Xueting Ren, Nan Wang, Ruina Zhou, Mengsha Chen, Yifan Cai, Shuai Lin, Hao Zhang, Xin Xie, Chengxue Dang, Shuqun Zhang, Zhangjian Zhou
Formato: article
Lenguaje:EN
Publicado: Frontiers Media S.A. 2021
Materias:
genomic instability
long non-coding RNAs
hepatocellular carcinoma
prognosis
immune infiltration
Genetics
QH426-470
Acceso en línea:https://doaj.org/article/3a7983a548fe4b899c8a0ab70c7721cb
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