High protein copy number is required to suppress stochasticity in the cyanobacterial circadian clock

Circadian clocks must maintain their fidelity despite stochasticity arising from finite protein copy numbers. Here, the authors show that a small cyanobacterium relies on an environmentally driven timer likely because its low protein copy numbers cannot support an accurate free-running clock.

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Autores principales:	Justin Chew, Eugene Leypunskiy, Jenny Lin, Arvind Murugan, Michael J. Rust
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/3a859e07eb4d4af4bc8e956db6348805
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spelling	oai:doaj.org-article:3a859e07eb4d4af4bc8e956db63488052021-12-02T15:34:07ZHigh protein copy number is required to suppress stochasticity in the cyanobacterial circadian clock10.1038/s41467-018-05109-42041-1723https://doaj.org/article/3a859e07eb4d4af4bc8e956db63488052018-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-05109-4https://doaj.org/toc/2041-1723Circadian clocks must maintain their fidelity despite stochasticity arising from finite protein copy numbers. Here, the authors show that a small cyanobacterium relies on an environmentally driven timer likely because its low protein copy numbers cannot support an accurate free-running clock.Justin ChewEugene LeypunskiyJenny LinArvind MuruganMichael J. RustNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Justin Chew Eugene Leypunskiy Jenny Lin Arvind Murugan Michael J. Rust High protein copy number is required to suppress stochasticity in the cyanobacterial circadian clock
description	Circadian clocks must maintain their fidelity despite stochasticity arising from finite protein copy numbers. Here, the authors show that a small cyanobacterium relies on an environmentally driven timer likely because its low protein copy numbers cannot support an accurate free-running clock.
format	article
author	Justin Chew Eugene Leypunskiy Jenny Lin Arvind Murugan Michael J. Rust
author_facet	Justin Chew Eugene Leypunskiy Jenny Lin Arvind Murugan Michael J. Rust
author_sort	Justin Chew
title	High protein copy number is required to suppress stochasticity in the cyanobacterial circadian clock
title_short	High protein copy number is required to suppress stochasticity in the cyanobacterial circadian clock
title_full	High protein copy number is required to suppress stochasticity in the cyanobacterial circadian clock
title_fullStr	High protein copy number is required to suppress stochasticity in the cyanobacterial circadian clock
title_full_unstemmed	High protein copy number is required to suppress stochasticity in the cyanobacterial circadian clock
title_sort	high protein copy number is required to suppress stochasticity in the cyanobacterial circadian clock
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/3a859e07eb4d4af4bc8e956db6348805
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High protein copy number is required to suppress stochasticity in the cyanobacterial circadian clock

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