Switching Between LC-ESI-MS/MS and EMIT Methods for Routine TDM of Valproic Acid in Pediatric Patients With Epilepsy: What Clinicians and Researchers Need to Know
Background: Valproic acid (VPA) is a widely used antiseizure medication and its dosing needs to be tailored individually through therapeutic drug monitoring (TDM) to avoid or prevent toxicity. Currently, immune-enzymatic assays such as Enzyme Multiplied Immunoassay Technique (EMIT), and Liquid Chrom...
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Formato: | article |
Lenguaje: | EN |
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Frontiers Media S.A.
2021
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Acceso en línea: | https://doaj.org/article/3a8a36eea831462aa353cf6299ea58f3 |
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