Total Maxillectomy and Free Flap Reconstruction in Hemodialysis Patients: Report of Two Cases

Summary:. Currently, an increasing number of patients are undergoing hemodialysis. However, little is known regarding the outcome or perioperative management of head and neck cancer reconstruction in patients undergoing hemodialysis. Here, we report two cases of patients with maxillary squamous cell...

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Autores principales: Kou Fujisawa, MD, Shimpei Miyamoto, MD, Yuki Saito, MD, Osamu Fukuoka, MD, Mutsumi Okazaki, MD
Formato: article
Lenguaje:EN
Publicado: Wolters Kluwer 2021
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Acceso en línea:https://doaj.org/article/3a8e1b8315bb4c1795ed05102defec6e
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spelling oai:doaj.org-article:3a8e1b8315bb4c1795ed05102defec6e2021-11-25T07:58:04ZTotal Maxillectomy and Free Flap Reconstruction in Hemodialysis Patients: Report of Two Cases2169-757410.1097/GOX.0000000000003922https://doaj.org/article/3a8e1b8315bb4c1795ed05102defec6e2021-11-01T00:00:00Zhttp://journals.lww.com/prsgo/fulltext/10.1097/GOX.0000000000003922https://doaj.org/toc/2169-7574Summary:. Currently, an increasing number of patients are undergoing hemodialysis. However, little is known regarding the outcome or perioperative management of head and neck cancer reconstruction in patients undergoing hemodialysis. Here, we report two cases of patients with maxillary squamous cell carcinoma undergoing hemodialysis. The patients underwent total maxillectomy and free abdominal flap transfer. A short-thread double-needle was used in one patient because arterial calcification and intimal dissection were observed during microvascular anastomosis. Maintenance hemodialysis was performed the day before and after the surgery. Nafamostat mesylate, an ultra-short acting anticoagulant, was used in the postoperative hemodialysis for 2–3 weeks to prevent bleeding. The flaps survived completely, and no major postoperative complications occurred in either case. One patient showed no evidence of disease at 1 year following the surgery, whereas the other patient died of cancer metastasis 6 months following the surgery. Although further standardization of perioperative hemodialysis management is needed, free flap reconstruction could be considered a safe and effective therapeutic strategy for patients with head and neck cancer undergoing hemodialysis.Kou Fujisawa, MDShimpei Miyamoto, MDYuki Saito, MDOsamu Fukuoka, MDMutsumi Okazaki, MDWolters KluwerarticleSurgeryRD1-811ENPlastic and Reconstructive Surgery, Global Open, Vol 9, Iss 11, p e3922 (2021)
institution DOAJ
collection DOAJ
language EN
topic Surgery
RD1-811
spellingShingle Surgery
RD1-811
Kou Fujisawa, MD
Shimpei Miyamoto, MD
Yuki Saito, MD
Osamu Fukuoka, MD
Mutsumi Okazaki, MD
Total Maxillectomy and Free Flap Reconstruction in Hemodialysis Patients: Report of Two Cases
description Summary:. Currently, an increasing number of patients are undergoing hemodialysis. However, little is known regarding the outcome or perioperative management of head and neck cancer reconstruction in patients undergoing hemodialysis. Here, we report two cases of patients with maxillary squamous cell carcinoma undergoing hemodialysis. The patients underwent total maxillectomy and free abdominal flap transfer. A short-thread double-needle was used in one patient because arterial calcification and intimal dissection were observed during microvascular anastomosis. Maintenance hemodialysis was performed the day before and after the surgery. Nafamostat mesylate, an ultra-short acting anticoagulant, was used in the postoperative hemodialysis for 2–3 weeks to prevent bleeding. The flaps survived completely, and no major postoperative complications occurred in either case. One patient showed no evidence of disease at 1 year following the surgery, whereas the other patient died of cancer metastasis 6 months following the surgery. Although further standardization of perioperative hemodialysis management is needed, free flap reconstruction could be considered a safe and effective therapeutic strategy for patients with head and neck cancer undergoing hemodialysis.
format article
author Kou Fujisawa, MD
Shimpei Miyamoto, MD
Yuki Saito, MD
Osamu Fukuoka, MD
Mutsumi Okazaki, MD
author_facet Kou Fujisawa, MD
Shimpei Miyamoto, MD
Yuki Saito, MD
Osamu Fukuoka, MD
Mutsumi Okazaki, MD
author_sort Kou Fujisawa, MD
title Total Maxillectomy and Free Flap Reconstruction in Hemodialysis Patients: Report of Two Cases
title_short Total Maxillectomy and Free Flap Reconstruction in Hemodialysis Patients: Report of Two Cases
title_full Total Maxillectomy and Free Flap Reconstruction in Hemodialysis Patients: Report of Two Cases
title_fullStr Total Maxillectomy and Free Flap Reconstruction in Hemodialysis Patients: Report of Two Cases
title_full_unstemmed Total Maxillectomy and Free Flap Reconstruction in Hemodialysis Patients: Report of Two Cases
title_sort total maxillectomy and free flap reconstruction in hemodialysis patients: report of two cases
publisher Wolters Kluwer
publishDate 2021
url https://doaj.org/article/3a8e1b8315bb4c1795ed05102defec6e
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