H5N1 Influenza Virus Pathogenesis in Genetically Diverse Mice Is Mediated at the Level of Viral Load

ABSTRACT The genotype of the host is one of several factors involved in the pathogenesis of an infectious disease and may be a key parameter in the epidemiology of highly pathogenic H5N1 influenza virus infection in humans. Gene polymorphisms may affect the viral replication rate or alter the host’s...

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Autores principales: Adrianus C. M. Boon, David Finkelstein, Ming Zheng, Guochun Liao, John Allard, Klaus Klumpp, Robert Webster, Gary Peltz, Richard J. Webby
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2011
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Acceso en línea:https://doaj.org/article/3a9487f42a7647bf9dbb2acaf2b7d349
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