Somatic Mutations in Exons 10, 11, and 16 of the RET Protooncogene in Medullary Thyroid Carcinoma Patients
Introduction: Medullary thyroid carcinoma (MTC) comprises nearly 5% of all cases of thyroid cancer (TC). Aberrant activation of RET (rearranged during transfection) signaling via somatic mutations is the basic molecular mechanism of MTC tumorigenicity. In this study, we determined the incidence of R...
Saved in:
Main Authors: | Elham Shakiba, Mehdi Hedayati, Ahmad Majd, Monireh Movahedi |
---|---|
Format: | article |
Language: | EN |
Published: |
Zabol University of Medical sciences
2020
|
Subjects: | |
Online Access: | https://doaj.org/article/3a996ca7460f4e99877fcbeee1b8fc32 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Modifier Role of Common <i>RET</i> Variants in Sporadic Medullary Thyroid Carcinoma
by: Anna Skalniak, et al.
Published: (2021) -
A case report of simultaneous medullary and papillary carcinoma of thyroid
by: Ziaolhagh Reza, et al.
Published: (2021) -
Serum Calcitonin-Negative Medullary Thyroid Carcinoma: A Case Series of 19 Patients in a Single Center
by: Sun Jung Kim, et al.
Published: (2021) -
Germline RET Leu56Met Variant Is Likely Not Causative of Multiple Endocrine Neoplasia Type 2
by: Anna Reimer Hansen, et al.
Published: (2021) -
Somatic Genomic Changes in the Formation of Differentiated Thyroid Carcinoma
by: Vidinov K., et al.
Published: (2020)