Somatic Mutations in Exons 10, 11, and 16 of the RET Protooncogene in Medullary Thyroid Carcinoma Patients

Introduction: Medullary thyroid carcinoma (MTC) comprises nearly 5% of all cases of thyroid cancer (TC). Aberrant activation of RET (rearranged during transfection) signaling via somatic mutations is the basic molecular mechanism of MTC tumorigenicity. In this study, we determined the incidence of R...

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Auteurs principaux: Elham Shakiba, Mehdi Hedayati, Ahmad Majd, Monireh Movahedi
Format: article
Langue:EN
Publié: Zabol University of Medical sciences 2020
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Accès en ligne:https://doaj.org/article/3a996ca7460f4e99877fcbeee1b8fc32
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