Small molecule electro-optical binding assay using nanopores

Nanopore detection of small molecules can be improved using molecular carriers, but separating a small analyte from the carrier signal can be challenging. Here the authors address this challenge using simultaneous electrical and optical readout in nanopore sensing to detect small molecules and quant...

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Autores principales:	Shenglin Cai, Jasmine Y. Y. Sze, Aleksandar P. Ivanov, Joshua B. Edel
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/3aa322cfb567432698be53e2febb90a6
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spelling	oai:doaj.org-article:3aa322cfb567432698be53e2febb90a62021-12-02T17:01:29ZSmall molecule electro-optical binding assay using nanopores10.1038/s41467-019-09476-42041-1723https://doaj.org/article/3aa322cfb567432698be53e2febb90a62019-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-09476-4https://doaj.org/toc/2041-1723Nanopore detection of small molecules can be improved using molecular carriers, but separating a small analyte from the carrier signal can be challenging. Here the authors address this challenge using simultaneous electrical and optical readout in nanopore sensing to detect small molecules and quantify binding affinities.Shenglin CaiJasmine Y. Y. SzeAleksandar P. IvanovJoshua B. EdelNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-9 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Shenglin Cai Jasmine Y. Y. Sze Aleksandar P. Ivanov Joshua B. Edel Small molecule electro-optical binding assay using nanopores
description	Nanopore detection of small molecules can be improved using molecular carriers, but separating a small analyte from the carrier signal can be challenging. Here the authors address this challenge using simultaneous electrical and optical readout in nanopore sensing to detect small molecules and quantify binding affinities.
format	article
author	Shenglin Cai Jasmine Y. Y. Sze Aleksandar P. Ivanov Joshua B. Edel
author_facet	Shenglin Cai Jasmine Y. Y. Sze Aleksandar P. Ivanov Joshua B. Edel
author_sort	Shenglin Cai
title	Small molecule electro-optical binding assay using nanopores
title_short	Small molecule electro-optical binding assay using nanopores
title_full	Small molecule electro-optical binding assay using nanopores
title_fullStr	Small molecule electro-optical binding assay using nanopores
title_full_unstemmed	Small molecule electro-optical binding assay using nanopores
title_sort	small molecule electro-optical binding assay using nanopores
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/3aa322cfb567432698be53e2febb90a6
work_keys_str_mv	AT shenglincai smallmoleculeelectroopticalbindingassayusingnanopores AT jasmineyysze smallmoleculeelectroopticalbindingassayusingnanopores AT aleksandarpivanov smallmoleculeelectroopticalbindingassayusingnanopores AT joshuabedel smallmoleculeelectroopticalbindingassayusingnanopores
_version_	1718382077001334784

Small molecule electro-optical binding assay using nanopores

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