Comparing the long-term impact on health care resources utilization and costs due to various single-piece acrylic monofocal intraocular lens implantation during cataract surgery: a cost-consequence analysis for the United Kingdom, Italy, and Denmark

Mukesh Dhariwal,1 Christine Bouchet,2 Shantanu Jawla3 1Global Health Economics & Outcomes Research, Alcon Laboratories, Inc., Fort Worth, TX, USA; 2Global Patient Access, Novartis Pharma AG, Basel, Switzerland; 3Patient Access Services, Novartis Healthcare Private Limited, Hyderabad, India...

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Autores principales:	Dhariwal M, Bouchet C, Jawla S
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2019
Materias:	AcrySof cost cystoid macular edema glaucoma Nd:YAG capsulotomy retinal detachment Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/3abac093e2604e36a3b6dfc83a66d249
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spelling	oai:doaj.org-article:3abac093e2604e36a3b6dfc83a66d2492021-12-02T05:43:39ZComparing the long-term impact on health care resources utilization and costs due to various single-piece acrylic monofocal intraocular lens implantation during cataract surgery: a cost-consequence analysis for the United Kingdom, Italy, and Denmark1177-5483https://doaj.org/article/3abac093e2604e36a3b6dfc83a66d2492019-01-01T00:00:00Zhttps://www.dovepress.com/comparing-the-long-term-impact-on-health-care-resources-utilization-an-peer-reviewed-article-OPTHhttps://doaj.org/toc/1177-5483Mukesh Dhariwal,1 Christine Bouchet,2 Shantanu Jawla3 1Global Health Economics & Outcomes Research, Alcon Laboratories, Inc., Fort Worth, TX, USA; 2Global Patient Access, Novartis Pharma AG, Basel, Switzerland; 3Patient Access Services, Novartis Healthcare Private Limited, Hyderabad, India Purpose: The objective of this study was to estimate the cost impact of neodymium-doped yttrium aluminum garnet (Nd:YAG) laser capsulotomy and its complications due to single-piece acrylic monofocal intraocular lenses (IOLs) in the healthcare setting of United Kingdom, Italy, and Denmark.Materials and methods: A hypothetical cost-consequence model was developed to estimate economic burden of Nd:YAG laser capsulotomy due to different single-piece acrylic monofocal IOLs. Cumulative incidence of Nd:YAG laser capsulotomy at 3 years after cataract surgery with five single-piece monofocal acrylic IOLs was sourced from retrospective data analysis of electronic medical records of cataract patients in the United Kingdom. Risk probability of post-Nd:YAG laser complications, ie, retinal detachment, glaucoma, and cystoid macular edema at 3 years was derived using published literature. Unit costs were taken from publicly available sources with all costs converted to euro (€). Number of cataract procedures per year for each country was sourced from Eurostat statistics.Results: For the estimated cataract procedures carried out nationally every year, single-piece monofocal hydrophobic AcrySof IOL was associated with substantially lower cases of Nd:YAG laser capsulotomy procedures and subsequent complications in 3 years after cataract surgery when compared to other single-piece monofocal acrylic IOLs. The total cost savings with the use of AcrySof over other IOLs in countries assessed ranged from €0.5 to €4.7 million (vs AMO Tecnis) and €2.1 to €17.9 million (vs Rayner C-/Super-flex).Conclusion: Incidence of Nd:YAG capsulotomy due to the choice of IOL could significantly affect healthcare budgets in the post-cataract surgery period. Our analysis indicates that single-piece monofocal AcrySof IOLs is the most cost-saving treatment option for health care systems when compared to other acrylic single-piece IOLs. Keywords: AcrySof, cost, Nd:YAG capsulotomy, cataract, PCO, IOLDhariwal MBouchet CJawla SDove Medical PressarticleAcrySofcostcystoid macular edemaglaucomaNd:YAG capsulotomyretinal detachmentOphthalmologyRE1-994ENClinical Ophthalmology, Vol Volume 13, Pp 169-176 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	AcrySof cost cystoid macular edema glaucoma Nd:YAG capsulotomy retinal detachment Ophthalmology RE1-994
spellingShingle	AcrySof cost cystoid macular edema glaucoma Nd:YAG capsulotomy retinal detachment Ophthalmology RE1-994 Dhariwal M Bouchet C Jawla S Comparing the long-term impact on health care resources utilization and costs due to various single-piece acrylic monofocal intraocular lens implantation during cataract surgery: a cost-consequence analysis for the United Kingdom, Italy, and Denmark
description	Mukesh Dhariwal,1 Christine Bouchet,2 Shantanu Jawla3 1Global Health Economics & Outcomes Research, Alcon Laboratories, Inc., Fort Worth, TX, USA; 2Global Patient Access, Novartis Pharma AG, Basel, Switzerland; 3Patient Access Services, Novartis Healthcare Private Limited, Hyderabad, India Purpose: The objective of this study was to estimate the cost impact of neodymium-doped yttrium aluminum garnet (Nd:YAG) laser capsulotomy and its complications due to single-piece acrylic monofocal intraocular lenses (IOLs) in the healthcare setting of United Kingdom, Italy, and Denmark.Materials and methods: A hypothetical cost-consequence model was developed to estimate economic burden of Nd:YAG laser capsulotomy due to different single-piece acrylic monofocal IOLs. Cumulative incidence of Nd:YAG laser capsulotomy at 3 years after cataract surgery with five single-piece monofocal acrylic IOLs was sourced from retrospective data analysis of electronic medical records of cataract patients in the United Kingdom. Risk probability of post-Nd:YAG laser complications, ie, retinal detachment, glaucoma, and cystoid macular edema at 3 years was derived using published literature. Unit costs were taken from publicly available sources with all costs converted to euro (€). Number of cataract procedures per year for each country was sourced from Eurostat statistics.Results: For the estimated cataract procedures carried out nationally every year, single-piece monofocal hydrophobic AcrySof IOL was associated with substantially lower cases of Nd:YAG laser capsulotomy procedures and subsequent complications in 3 years after cataract surgery when compared to other single-piece monofocal acrylic IOLs. The total cost savings with the use of AcrySof over other IOLs in countries assessed ranged from €0.5 to €4.7 million (vs AMO Tecnis) and €2.1 to €17.9 million (vs Rayner C-/Super-flex).Conclusion: Incidence of Nd:YAG capsulotomy due to the choice of IOL could significantly affect healthcare budgets in the post-cataract surgery period. Our analysis indicates that single-piece monofocal AcrySof IOLs is the most cost-saving treatment option for health care systems when compared to other acrylic single-piece IOLs. Keywords: AcrySof, cost, Nd:YAG capsulotomy, cataract, PCO, IOL
format	article
author	Dhariwal M Bouchet C Jawla S
author_facet	Dhariwal M Bouchet C Jawla S
author_sort	Dhariwal M
title	Comparing the long-term impact on health care resources utilization and costs due to various single-piece acrylic monofocal intraocular lens implantation during cataract surgery: a cost-consequence analysis for the United Kingdom, Italy, and Denmark
title_short	Comparing the long-term impact on health care resources utilization and costs due to various single-piece acrylic monofocal intraocular lens implantation during cataract surgery: a cost-consequence analysis for the United Kingdom, Italy, and Denmark
title_full	Comparing the long-term impact on health care resources utilization and costs due to various single-piece acrylic monofocal intraocular lens implantation during cataract surgery: a cost-consequence analysis for the United Kingdom, Italy, and Denmark
title_fullStr	Comparing the long-term impact on health care resources utilization and costs due to various single-piece acrylic monofocal intraocular lens implantation during cataract surgery: a cost-consequence analysis for the United Kingdom, Italy, and Denmark
title_full_unstemmed	Comparing the long-term impact on health care resources utilization and costs due to various single-piece acrylic monofocal intraocular lens implantation during cataract surgery: a cost-consequence analysis for the United Kingdom, Italy, and Denmark
title_sort	comparing the long-term impact on health care resources utilization and costs due to various single-piece acrylic monofocal intraocular lens implantation during cataract surgery: a cost-consequence analysis for the united kingdom, italy, and denmark
publisher	Dove Medical Press
publishDate	2019
url	https://doaj.org/article/3abac093e2604e36a3b6dfc83a66d249
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Comparing the long-term impact on health care resources utilization and costs due to various single-piece acrylic monofocal intraocular lens implantation during cataract surgery: a cost-consequence analysis for the United Kingdom, Italy, and Denmark

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