EXPERIMENTAL STUDY ON SOME PROTECTIVE METHODS AGAINST HYDATID CYST INFECTION IN MICE

Experimental study albion mice as a host was conducted in on attempt to inactivate the larval stage of Echinococcus granulosus by formalin treatment. Animals were divided into three groups. The first group was inoculated subcutaneously with alive ovine hydatid protoscolices , whereas the second gro...

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Autores principales:	I. T. AL- Sultan, E. R. AL- Kanany
Formato:	article
Lenguaje:	EN
Publicado:	University of Baghdad, College of Veterinary Medicine 2000
Materias:	MICE HYDATID CYST INFECTION Veterinary medicine SF600-1100
Acceso en línea:	https://doaj.org/article/3ac2acfc101e4ac79618889a1db315bd
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spelling	oai:doaj.org-article:3ac2acfc101e4ac79618889a1db315bd2021-11-09T11:36:39ZEXPERIMENTAL STUDY ON SOME PROTECTIVE METHODS AGAINST HYDATID CYST INFECTION IN MICE10.30539/ijvm.v24i2.11751609-56932410-7409https://doaj.org/article/3ac2acfc101e4ac79618889a1db315bd2000-12-01T00:00:00Zhttps://jcovm.uobaghdad.edu.iq/index.php/Iraqijvm/article/view/1175https://doaj.org/toc/1609-5693https://doaj.org/toc/2410-7409 Experimental study albion mice as a host was conducted in on attempt to inactivate the larval stage of Echinococcus granulosus by formalin treatment. Animals were divided into three groups. The first group was inoculated subcutaneously with alive ovine hydatid protoscolices , whereas the second group was inoculated similarly with 0.75% formalin- treated protoscolices. The rhird group was remained as negative control. a comparison was held between the three groups from haematological , immunological and histopathological points of view. The haematological picture revealed lymphopenia, eosinophilia and neutrophilia in both treated groups of mice. Infected mice in groups 1 and 2 responded subcutaneous injection of the antigen by production of antibodies detected by indirect haemagglutination test. Similar responses did not occur in noninfected control mice. Pathologically, results showed that the cellular were concentrated at the site of inoculation and at the draining lymph nodes without spreading to other organs. The formalinized protoscolices failed to induce development or formation of any cysts at the site of inoculation , in comparison with live protoscolices . The challenge of both treated groups at 4 weeks post primary infection showed that 80% of the infected and vaccinated animals resisted infection . I. T. AL- SultanE. R. AL- KananyUniversity of Baghdad, College of Veterinary MedicinearticleMICEHYDATID CYST INFECTIONVeterinary medicineSF600-1100ENThe Iraqi Journal of Veterinary Medicine, Vol 24, Iss 2 (2000)
institution	DOAJ
collection	DOAJ
language	EN
topic	MICE HYDATID CYST INFECTION Veterinary medicine SF600-1100
spellingShingle	MICE HYDATID CYST INFECTION Veterinary medicine SF600-1100 I. T. AL- Sultan E. R. AL- Kanany EXPERIMENTAL STUDY ON SOME PROTECTIVE METHODS AGAINST HYDATID CYST INFECTION IN MICE
description	Experimental study albion mice as a host was conducted in on attempt to inactivate the larval stage of Echinococcus granulosus by formalin treatment. Animals were divided into three groups. The first group was inoculated subcutaneously with alive ovine hydatid protoscolices , whereas the second group was inoculated similarly with 0.75% formalin- treated protoscolices. The rhird group was remained as negative control. a comparison was held between the three groups from haematological , immunological and histopathological points of view. The haematological picture revealed lymphopenia, eosinophilia and neutrophilia in both treated groups of mice. Infected mice in groups 1 and 2 responded subcutaneous injection of the antigen by production of antibodies detected by indirect haemagglutination test. Similar responses did not occur in noninfected control mice. Pathologically, results showed that the cellular were concentrated at the site of inoculation and at the draining lymph nodes without spreading to other organs. The formalinized protoscolices failed to induce development or formation of any cysts at the site of inoculation , in comparison with live protoscolices . The challenge of both treated groups at 4 weeks post primary infection showed that 80% of the infected and vaccinated animals resisted infection .
format	article
author	I. T. AL- Sultan E. R. AL- Kanany
author_facet	I. T. AL- Sultan E. R. AL- Kanany
author_sort	I. T. AL- Sultan
title	EXPERIMENTAL STUDY ON SOME PROTECTIVE METHODS AGAINST HYDATID CYST INFECTION IN MICE
title_short	EXPERIMENTAL STUDY ON SOME PROTECTIVE METHODS AGAINST HYDATID CYST INFECTION IN MICE
title_full	EXPERIMENTAL STUDY ON SOME PROTECTIVE METHODS AGAINST HYDATID CYST INFECTION IN MICE
title_fullStr	EXPERIMENTAL STUDY ON SOME PROTECTIVE METHODS AGAINST HYDATID CYST INFECTION IN MICE
title_full_unstemmed	EXPERIMENTAL STUDY ON SOME PROTECTIVE METHODS AGAINST HYDATID CYST INFECTION IN MICE
title_sort	experimental study on some protective methods against hydatid cyst infection in mice
publisher	University of Baghdad, College of Veterinary Medicine
publishDate	2000
url	https://doaj.org/article/3ac2acfc101e4ac79618889a1db315bd
work_keys_str_mv	AT italsultan experimentalstudyonsomeprotectivemethodsagainsthydatidcystinfectioninmice AT eralkanany experimentalstudyonsomeprotectivemethodsagainsthydatidcystinfectioninmice
_version_	1718441098695671808

EXPERIMENTAL STUDY ON SOME PROTECTIVE METHODS AGAINST HYDATID CYST INFECTION IN MICE

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