Early laparoscopic cholecystectomy after percutaneous transhepatic gallbladder drainage for acute cholecystitis

Abstract There is no consensus on the optimal timing of laparoscopic cholecystectomy (LC) after percutaneous transhepatic gallbladder drainage (PTGBD) for patients with acute cholecystitis (AC). We retrospectively evaluated patients who underwent LC after PTGBD between 1 February 2016 and 1 February...

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Autores principales: Yunxiao Lyu, Ting Li, Bin Wang, Yunxiao Cheng
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Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/3ac53112c9f24157a21f9f14bdbf44ce
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spelling oai:doaj.org-article:3ac53112c9f24157a21f9f14bdbf44ce2021-12-02T13:57:25ZEarly laparoscopic cholecystectomy after percutaneous transhepatic gallbladder drainage for acute cholecystitis10.1038/s41598-021-82089-42045-2322https://doaj.org/article/3ac53112c9f24157a21f9f14bdbf44ce2021-01-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-82089-4https://doaj.org/toc/2045-2322Abstract There is no consensus on the optimal timing of laparoscopic cholecystectomy (LC) after percutaneous transhepatic gallbladder drainage (PTGBD) for patients with acute cholecystitis (AC). We retrospectively evaluated patients who underwent LC after PTGBD between 1 February 2016 and 1 February 2020. We divided patients into three groups according to the interval time between PTGBD and LC as follows: Group I (within 1 week), (Group II, 1 week to 1 month), and Group III (> 1 month) and analyzed patients’ perioperative outcomes. We enrolled 100 patients in this study (Group I, n = 22; Group II, n = 30; Group III, n = 48). We found no significant difference between the groups regarding patients’ baseline characteristics and no significant difference regarding operation time and estimated blood loss (p = 0.69, p = 0.26, respectively). The incidence of conversion to open cholecystectomy was similar in the three groups (p = 0.37), and we found no significant difference regarding postoperative complications (p = 0.987). Group I had shorter total hospital stays and medical costs (p = 0.005, p < 0.001, respectively) vs Group II and Group III. Early LC within 1 week after PTGBD is safe and effective, with comparable intraoperative outcomes, postoperative complications, and conversion rates to open cholecystectomy. Furthermore, early LC could decrease postoperative length of hospital stay and medical costs.Yunxiao LyuTing LiBin WangYunxiao ChengNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-6 (2021)
institution DOAJ
collection DOAJ
language EN
topic Medicine
R
Science
Q
spellingShingle Medicine
R
Science
Q
Yunxiao Lyu
Ting Li
Bin Wang
Yunxiao Cheng
Early laparoscopic cholecystectomy after percutaneous transhepatic gallbladder drainage for acute cholecystitis
description Abstract There is no consensus on the optimal timing of laparoscopic cholecystectomy (LC) after percutaneous transhepatic gallbladder drainage (PTGBD) for patients with acute cholecystitis (AC). We retrospectively evaluated patients who underwent LC after PTGBD between 1 February 2016 and 1 February 2020. We divided patients into three groups according to the interval time between PTGBD and LC as follows: Group I (within 1 week), (Group II, 1 week to 1 month), and Group III (> 1 month) and analyzed patients’ perioperative outcomes. We enrolled 100 patients in this study (Group I, n = 22; Group II, n = 30; Group III, n = 48). We found no significant difference between the groups regarding patients’ baseline characteristics and no significant difference regarding operation time and estimated blood loss (p = 0.69, p = 0.26, respectively). The incidence of conversion to open cholecystectomy was similar in the three groups (p = 0.37), and we found no significant difference regarding postoperative complications (p = 0.987). Group I had shorter total hospital stays and medical costs (p = 0.005, p < 0.001, respectively) vs Group II and Group III. Early LC within 1 week after PTGBD is safe and effective, with comparable intraoperative outcomes, postoperative complications, and conversion rates to open cholecystectomy. Furthermore, early LC could decrease postoperative length of hospital stay and medical costs.
format article
author Yunxiao Lyu
Ting Li
Bin Wang
Yunxiao Cheng
author_facet Yunxiao Lyu
Ting Li
Bin Wang
Yunxiao Cheng
author_sort Yunxiao Lyu
title Early laparoscopic cholecystectomy after percutaneous transhepatic gallbladder drainage for acute cholecystitis
title_short Early laparoscopic cholecystectomy after percutaneous transhepatic gallbladder drainage for acute cholecystitis
title_full Early laparoscopic cholecystectomy after percutaneous transhepatic gallbladder drainage for acute cholecystitis
title_fullStr Early laparoscopic cholecystectomy after percutaneous transhepatic gallbladder drainage for acute cholecystitis
title_full_unstemmed Early laparoscopic cholecystectomy after percutaneous transhepatic gallbladder drainage for acute cholecystitis
title_sort early laparoscopic cholecystectomy after percutaneous transhepatic gallbladder drainage for acute cholecystitis
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/3ac53112c9f24157a21f9f14bdbf44ce
work_keys_str_mv AT yunxiaolyu earlylaparoscopiccholecystectomyafterpercutaneoustranshepaticgallbladderdrainageforacutecholecystitis
AT tingli earlylaparoscopiccholecystectomyafterpercutaneoustranshepaticgallbladderdrainageforacutecholecystitis
AT binwang earlylaparoscopiccholecystectomyafterpercutaneoustranshepaticgallbladderdrainageforacutecholecystitis
AT yunxiaocheng earlylaparoscopiccholecystectomyafterpercutaneoustranshepaticgallbladderdrainageforacutecholecystitis
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