Synthetic multivalent antifungal peptides effective against fungi.

Synthetic multivalent antifungal peptides effective against fungi.

Taking advantage of the cluster effect observed in multivalent peptides, this work describes antifungal activity and possible mechanism of action of tetravalent peptide (B4010) which carries 4 copies of the sequence RGRKVVRR through a branched lysine core. B4010 displayed better antifungal propertie...

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Autores principales: Rajamani Lakshminarayanan, Shouping Liu, Jianguo Li, Muruganantham Nandhakumar, Thet Tun Aung, Eunice Goh, Jamie Ya Ting Chang, Padhmanaban Saraswathi, Charles Tang, Siti Radiah Binte Safie, Lim Yih Lin, Howard Riezman, Zhou Lei, Chandra S Verma, Roger W Beuerman
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2014
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/3ac6c677bc2d44b58f3161d4fd26c57e
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